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Table 3 Risk factors for neonatal bacterial eye infection

From: Does azithromycin given to women in labour decrease ocular bacterial infection in neonates? A double-blind, randomized trial

Characteristic Both trial arms Placebo arm only
N n (%) OR (95%CI) p-value N n (%) OR (95%CI) p-value
>18 h membrane rupture to birth
 No 384 2.3 1   205 2.9 1  
 Yes 459 2.6 1.12 (0.47,2.68) 0.829 219 4.6 1.59 (0.57,4.45) 0.45
Gender
 Female 405 1.7 1   198 2.5 1  
 Male 438 3.2 1.88 (0.75,4.70) 0.191 226 4.9 1.97 (0.67,5.79) 0.307
Apgar score
 0 12 0.0 NA   6 0.0 NA  
 1–6 13 0.0 NA   5 0.0 NA  
 7–10 810 2.6 NA 1 408 3.9 NA 1
Low birth-weight (<2.5 kg)
 No 786 2.5 1   392 3.8 1  
 Yes 55 1.8 0.71 (0.09,5.39) 1 30 3.3 0.87 (0.11,6.79) 1
Bacteria in the vaginal swab prior to intervention
 No 615 2.3 1   302 3.3 1  
 Yes 228 3.1 1.36 (0.54,3.41) 0.468 122 4.9 1.51 (0.54,4.25) 0.412
Season
 Dry 557 2.0 1   280 2.9 1  
 Wet 286 3.5 1.80 (0.75,4.29) 0.242 144 5.6 2.00 (0.73,5.44) 0.184
Tetracycline at birth
 No 99 3.0 1   47 6.4 1  
 Yes 743 2.4 0.79 (0.23,2.75) 0.728 377 3.4 0.52 (0.14,1.91) 0.404
Mothers’ years of schooling
  < 1 year 424 2.6 1   210 3.8 1  
 1+ years 398 2.5 0.97 (0.41,2.30) 1 203 3.9 1.04 (0.38,2.81) 1
Ethnicity
 Madinka 352 2.3 1   189 3.7 1 0.691
 Wollof 94 1.1 0.46 (0.06,3.74)   47 2.1 0.57 (0.07,4.71) 0.691
 Jola 127 5.5 2.51 (0.89,7.06)   59 6.8 1.89 (0.53,6.70) 0.691
 Fula 144 2.8 1.23 (0.36,4.15)   66 4.5 1.24 (0.31,4.93) 0.691
 Other 106 0.9 0.41 (0.05,3.31) 0.23 56 1.8 0.47(0.06,3.93) 0.691