Dengue virus infection-enhancement activity in neutralizing antibodies of healthy adults before dengue season as determined by using FcγR-expressing cells

Table 1 Characteristic of the study population

Variable		Total (n)	DENV IgG positive ^a N (%)	Crude OR	95% C.I	p-value
Before dengue season		100	34 ^c (34.00)
Age group (years)	20–30	74	20 (58.82)	1.00		0.05
	30–40	22	12 (35.29)	3.24	1.21–8.66
	≥40	4	2 (5.88)	2.70	0.35–20.48
Gender	Male	27	11 (32.35)	1.00
Gender	Female	73	23 (67.65)	0.67	0.27–1.68	0.39
DENV IgM ^b	Negative	94	34 ^c (100.00)
DENV IgM ^b	Positive	6	0 (00.00)
After dengue season		100	52 ^d (52.00)
Age group (years)	20–30	74	35 (67.31)	1.00		0.25
	30–40	22	14 (26.92)	1.95	0.73–5.20
	≥40	4	3 (5.77)	3.34	0.33–33.63
Gender	Male	27	19 (36.54)	1.00		0.02
Gender	Female	73	33 (63.46)	0.34	0.13–0.92
DENV IgM ^b	Negative	82	40 (76.92)	1.00
DENV IgM ^b	Positive	18	12 (23.08)	2.10	0.71–6.23	0.17

Crude OR Crude odds ratio, 95% C.I 95% confidence interval
^a DENV IgG result was as determined by using in-house DENV IgG Elisa and DENV IgG indirect Elisa (Panbio)
^b DENV IgM result was determined by using an in-house DENV IgM Elisa test
^c These 34 individuals were considered as asymptomatic secondary infection (S.I) cases
^d Out of 52 individuals, 34 had DENV IgG before the dengue season and continue to have elevated DENV IgG after the dengue season, the remain 18 had only DENV IgG after the dengue season

ISSN: 1471-2334