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Table 1 Baseline characteristics of patients included in the study

From: The rs738409 polymorphism of the PNPLA3 gene is associated with hepatic steatosis and fibrosis in Brazilian patients with chronic hepatitis C

Characteristics

Total

N

290

Age (mean±SD)

54.9±12.1

Male gender

124 (42.8%)

Ethnicity/color

 White

226 (77.9%)

Pardo

43 (14.8%)

 Black

21 (7.2%)

Alcohol > 20 g/day

55(19.3%)

BMI (mean±SD)

27.1±6.1

Glucose (mean±SD)

93.1±49.4

Insulin (mean±SD)

15.2±32.2

ALT (mean±SD)

62.3±49.4

AST (mean±SD)

49.8±38.1

Total cholesterol (mean±SD)

173.9±39.8

LDL-C (mean±SD)

95.5±32.8

HDL-C (mean±SD)

55.3±18.5

VLDL-C (mean±SD)

23.9±20.9

Triglycerides (mean±SD)

109.3±66.8

Hepatic steatosis ≥ 5%

143 (49.3%)

Liver fibrosis (Metavir ≥ F3)

58 (20%)

HCV genotype 3

45 (15.7%)

PNPLA3 rs738409

 CC

133 (45.9%)

 CG

63 (21.7%)

 GG

94 (32.4%)

TM6F2 rs58542926

 CC

261 (90%)

 CT

29 (10%)

  1. Abbreviations: BMI body mass index, ALT alanine aminotransferase, AST aspartate aminotransferase, LDL-C low-density lipoprotein-cholesterol, HDL-C high-density lipoprotein-cholesterol, VLDL very-low-density lipoprotein-cholesterol