From: A clinical tool to predict Plasmodium vivax recurrence in Malaysia
Patient characteristic (reference) | Recurrence (n = 127) | Beta | Odds Ratio | 95% CI | P-value | |
---|---|---|---|---|---|---|
Age (≥ 27 years) | 83 | – | 1.00 | – | – | – |
< 27 years | 44 | 0.62 | 1.90 | 1.14 | 3.17 | 0.00 |
Gender (Female) | 52 | – | 1.00 | – | – | – |
Male | 75 | 0.92 | 0.40 | 0.28 | 0.58 | 0.00 |
Malaysian (Non-Malaysians) | 16 | – | 1.00 | – | – | – |
Malaysians | 111 | 1.35 | 3.87 | 2.30 | 6.51 | 0.00 |
Region (Non-Western Pacific) | 13 | – | 1.00 | – | – | – |
Western Pacific | 114 | 1.37 | 3.95 | 2.28 | 6.82 | 0.00 |
G6PD (Normal) | 125 | – | 1.00 | – | – | – |
Deficient | 2 | −1.18 | 0.31 | 0.07 | 1.27 | 0.12 |
Pregnant (Non-pregnant) | 44 | – | 1.00 | – | – | – |
Pregnant | 8 | 0.89 | 2.44 | 1.05 | 5.66 | 0.04 |
Case locality (Urban) | 0 | – | 1.00 | – | – | – |
Rural | 104 | 1.33 | 3.77 | 1.89 | 7.55 | 0.00 |
Agriculture | 23 | 0.70 | 2.01 | 0.84 | 4.77 | 0.11 |
Status of case locality (Free) | 32 | – | 1.00 | – | – | – |
Prone | 0 | −1.08 | 0.34 | 0.08 | 1.43 | 0.14 |
Problematic | 95 | 1.03 | 2.73 | 1.78 | 1.43 | 0.00 |
Disease characteristic (reference) | ||||||
Length of stay (days) (range) | 1–14 days | −0.01 | 0.99 | 0.95 | 1.04 | 0.68 |
Previous infection (no) | 97 | – | 1.00 | – | – | – |
Yes | 30 | −0.27 | 0.76 | 0.48 | 1.21 | 0.25 |
Presence of gametocyte (negative) | 37 | – | 1.00 | – | – | – |
Positive | 90 | 0.24 | 1.27 | 0.84 | 1.92 | 0.27 |
Gametocyte (<80 parasite/μL) | 44 | – | 1.00 | – | – | – |
≥ 80 parasite/μL | 83 | 0.47 | 1.60 | 1.07 | 2.40 | 0.02 |
Asexual (<2700 parasite/μL) | 60 | – | 1.00 | – | – | – |
≥ 2700 parasite/μL | 67 | 0.068 | 1.07 | 0.74 | 1.54 | 0.71 |
Week onset (weeks) | 1–52 | 0.00 | 1.00 | 0.98 | 1.01 | 0.49 |
Severity (Non-severe) | 127 | – | 1.00 | – | – | – |
Severe infection | 0 | −18.52 | 0.00 | 0.00 | . | 1.00 |
Malaria transmission type | ||||||
(Non-indigenous) | 10 | – | 1.00 | – | – | – |
Indigenous | 107 | 1.21 | 3.35 | 2.06 | 5.50 | 0.00 |
Relapse before | 10 | 1.50 | 4.50 | 1.82 | 11.08 | 0.11 |
Treatment characteristic (reference) | ||||||
Treatment type (ACT plus PQ) | 106 | – | 1.00 | – | – | – |
CP plus PQ | 21 | 0.99 | 2.70 | 1.66 | 4.39 | 0.00 |
Status of treatment (Complete) | 125 | – | 1.00 | – | – | – |
Incomplete | 2 | 1.445 | 4.242 | 0.90 | 20.02 | 0.068 |