Gene locus | Band | Gene region/mutation |
aRIF monoresistant |
bINH monoresistant |
cMDR |
---|
rpoB
| | | | | |
| WT1 | 506–509 | | | |
| WT2 | 510–513 | | | |
| WT3 | 513–517 | | |
d1 |
| WT4 | 516–519 | | | |
| WT5 | 518–522 | | | |
| WT6 | 521–525 | | | |
| WT7 | 526–529 | | |
d3 |
| WT8 | 530–533 | 1 | | 1 |
| MUT1 | D516V | | | 6 |
| MUT2A | H526Y | | |
d3 |
| MUT2B | H526D | | | |
| MUT3 | S531 L | 1 | | 1 |
katG
| | | | | |
| WT | 315 | |
d11 |
d4 |
| MUT1 | S315 T1 | | 14 | 10 |
| MUT2 | S315 T2 | | | |
inhA
| | | | | |
| WT1 | −15/−16 | |
d4 |
d1 |
| WT2 | −8 | | |
d1 |
| MUT1 | C15T | |
d4 |
d1 |
| MUT2 | A16G | | | |
| MUT3A | T8C | | | 6 |
| MUT3B | T8A | | | |
-
WT wild type band, MUT mutant band, RIF rifampicin, INH isoniazid, MDR multi-drug resistance
-
aIsolates with mutation(s) in the rpoB gene and none in the inhApro or katG gene
-
bIsolates with mutation(s) in the inhApro region and/or in the katG gene, with no mutation in the rpoB gene
-
cIsolates with mutations in the rpoB gene and inhApro and/or katG gene
-
dNumber of isolates that had presence of mutation band and the absence of corresponding wild type band