Skip to main content

Table 2 Clinical data of pandemic and postpandemic patients

From: ICU-treated influenza A(H1N1) pdm09 infections more severe post pandemic than during 2009 pandemic: a retrospective analysis

Variables 2009–2010 Pandemic (n = 16) 2012–2016 Postpandemic (n = 60) p value
Delay from symptoms to hospital admission, hours 108.0 (48–168) 72 (24–168) 0.37
Delay from hospital admission to ICU admission, days 1.9 (1.12–4.78) 1.04 (0.07–2.18) 0.25
Principal symptoms
 fever 10 (66.7) 43(71.7) 0.06
 dyspnea 10 (62.5) 52 (86.7) 0.037
 cough 11 (68.8) 28 (46.7) 0.16
 gastrointestinal 5 (31.3) 13 (21.7) 0.51
 neurological 1 (6.3) 15 (25) 0.17
PaO2/FiO2, kPa 33.4 (16.5–40.6) 26.3 (15.0–42.6) 0.41
Pneumonia on chest x-ray 11 (68.8) 53 (88.3) 0.11
 Bilateral opacities 11 (100.0) 49 (92.5) 0.16
ARDS    0.69
 No 5 (31.3) 17 (28.3)  
 Mild 2 (12.5) 3 (5.0)  
 Moderate 3 (18.8) 14 (23.3)  
 Severe 6 (37.5) 26 (43.3)  
Presence of bacteremia on admission 0 5 (10) 0.33
Mixed bacterial infection 7 (43.8) 9 (15) 0.033
Antiviral treatment on ICU admission 13 (81.3) 45 (75) 0.75
Bacterial antibiotics 15 (93.8) 48 (82) 0.48
  1. ARDS acute respiratory distress syndrome, ICU intensive care unit
  2. PaO2/FiO2 ratio is the ratio of arterial oxygen partial pressure to fractional inspired oxygen
  3. Values are presented as median (25th–75th percentile) or as number (percentage) of patients