Antibiotic Prescribing Decision Category
|
Control
|
Intervention
|
Total
|
---|
number
|
percent of control arm
|
number
|
percent intervention arm
|
---|
Continue
|
128
|
60.7
|
165
|
49.4
|
293
|
De-escalate
|
5
|
2.4
|
6
|
1.8
|
11
|
Escalate
|
4
|
1.9
|
26
|
7.8
|
30
|
Start
|
1
|
0.5
|
17
|
5.1
|
18
|
Stop
|
7
|
3.3
|
15
|
4.5
|
22
|
Remain off antibiotics
|
51
|
24.1
|
95
|
28.4
|
146
|
Missing data about decision
|
15
|
7.1
|
10
|
3.0
|
25
|
Total
|
211
| |
334
| |
545
|
- Control arm de-escalate: 2 stop ≥1 antimicrobial, 3 substitution of Beta-lactam with narrower spectrum Beta-lactam. Intervention arm de-escalate: 2 stop ≥1 antimicrobial, 2 substitution of Beta-lactam with narrower spectrum Beta-lactam, 2 substitution of Beta-lactam with narrower spectrum Beta-lactam and atypical agent was stopped. Control arm escalate: 4 add antibiotic to existing antibiotics (all agents against atypical pneumonia). Intervention arm escalate: 19 add antibiotics to existing antibiotics (14 agents against atypical pneumonia, 5 addition of agents against ‘typical pneumonia’ to atypical agent e.g. Beta-lactam or teicoplanin with ciprofloxacin if penicillin allergic), 7 substitution of Beta-lactam with broader spectrum Beta-lactam