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Table 2 Genotypes and alleles frequencies of FoxP3 gene SNPs in the cases and controls in relation to susceptibility to TB

From: G allele at −924 A > G position of FoxP3 gene promoter as a risk factor for tuberculosis

Position Gender
(No)
Genotype/Allele Controls (%)No TB patient
No (%)
Odd Ratioa
(95% CI)
Pb
FoxP3
−3279 A > C
Female AA
AC
CC
38 (53.2)
20 (28.1)
13 (18.3)
43 (51.1)
15 (17.8)
26 (30.9)
1:00 (Reference)c
0.56 (0.25 ± 1.2)
1.5 (0.67 ± 3.35)
0.1
Male A
C
65 (58.03)
47 (41.9)
64 (64.6)
35 (35.3)
1:00 (Reference)
1.3 (0.75 ± 2.3)
0.3
Total A
C
161 (63.3)
93 (36.6)
165 (61.7)
102 (38.2)
1:00 (Reference)
0.93 (0.65 ± 1.3)
0.7
FoxP3
−924 A > G
Female AA
AG
GG
34 (47.8)
14 (19.7)
23 (32.3)
19 (22.6)
22 (26.19)
43 (51.1)
1:00 (Reference)
0.29 (0.14 ± 0.63)
0.35 (0.14 ± 0.85)
0.005
Male A
G
73 (65.1)
39 (34.8)
48 (48.4)
51 (51.5)
1:00 (Reference)
3.42 (2.17 ± 5.39)
0.01
Total A
G
155 (61)
99 (39)
108 (40.4)
159 (59.5)
1:00 (Reference)
0.43(0.3 ± 0.61)
0.00
  1. aLogistic regression analyses were used for calculating odds ratios with 95% confidence interval
  2. b P value was determined by x2 test (for genotype) or Fisher exact test (for alleles) from a 2 × 2 and 2 × 3 contingency table
  3. cThe first allele or genotype is considered as reference