Table 1 Metrics considered for inclusion in SCORE morbidity cohort studies

Recommended for study, and included in the cohort evaluation protocol:

Anthropometric measures: age-standardized height, weight, body mass index (BMI), mid-upper arm circumference (MUAC) [16,17,18]

 Blood hemoglobin [3, 13,14,15]

 Exercise tolerance measured by 20-m shuttle run (beep) test [23,24,25,26]

 Health-related quality-of-life, measured by standardized PedsQL survey instrument [27, 28]

 Ultrasonography of the abdomen and liver (S. mansoni) or of the kidneys and bladder (S. haematobium), using standardized protocols [29, 30]

Considered, but not selected for study:

Individual-level outcomes

 Indicators of the mechanism for anemia: Zinc protoporphyrin, ferritin, hepcidin, C-reactive protein, Interleukin-6 [14, 31, 32]

 Volitional activity (e.g., as measured by accelerometers, fitness trackers) [33, 34]

 Attention span [19, 35]

 School performance, school completion rates [19]

 Serologic measures of collagen metabolism [36]

 Urine abnormalities, e.g., albuminuria, hematuria [3, 37]

 Eosinophilic cationic protein (ECP) in urine [38]

Household or Population-level outcomes

 Changes in religious participation [39]

 Health system utilization [40]

 Household income, productivity, work yield [22]

 Community fertility and birth outcomes [41, 42]

 Vaccine responses in babies [43]