Fig. 2

A compilation of two photomicrographs from the bone marrow biopsy with a Hematoxylin/Eosin (H&E) stain. In image a, a low-power image, the hypocellularity of the marrow (considering the patient’s young age) is highlighted. In image b, a high-power image, several hemophagocytic histiocytes can be seen. Both have a saccular appearance (their nuclei are highlighted by the black-colored arrow), dilated by phagocytosed marrow elements (whose partially-digested nuclei are highlighted with the white-colored arrow). H&E biopsy stains are prepared on formalin-fixed paraffin embedded bone marrow biopsy materials that are briefly decalcified in formic acid