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Table 1 Accuracy of Bioeasy™ rapid immunochromatographic test at point of care and in the laboratory

From: Accuracy and reliability of an NS1 rapid immunochromatographic test for DENV-1 diagnosis at point of care and in the laboratory

 

Readings at 15’

Readings at 30’

Whole blood/POCa

Serum/Laboratoryb

Whole blood/POCa

Serum/Laboratoryb

Sensitivity

76.7%c

82.2%c

78.3%c

84.9%c

(95%CI)

(68.0–84.1)

(74.1–88.6)

(69.9–85.3)

(77.2–90.8)

Specificity

87.0%d

100.0%d

87.5%d

95.8%d

(95% CI)

(66.4–97.2)

(85.8–100.0)

(67.6–97.3)

(78.9–99.9)

PPV

96.7%

100.0%

96.9%

99.0%

(95%CI)

(90.8–99.3)

(96.3% - 100.0)

(91.2–99.4)

(95.4–99.8)

NPV

42.6%

53.3%

44.7%

56.1%

(95%CI)

(28.3–57.8)

(37.9–68.3)

(30.2–59.9)

(39.8–71.5)

LR+

5.9

19.8e

6.27

20.4

(95%CI)

(2.0–17.0)

(2.9–135.1)

(2.2–18.1)

(3.0–139.0)

LR-

0.27

0.18

0.25

0.16

(95%CI)

(0.19–0.39)

(0.12–0.26)

(0.17–0.36)

(0.10–0.24)

  1. POC point of care, 95% CI 95% confidence interval, PPV positive predictive value, NPV negative predictive value, LR+ positive likelihood ratio, LR- negative likelihood ratio
  2. aPerformed with whole blood
  3. bPerformed with serum
  4. cP-value <0.01
  5. dP-value >0.05 of χ2 McNemar test
  6. eLR+ calculated using 97.9% specificity