Table 3 Resistance for 1st line anti-TB drugs among M.tuberculosis isolates from presumed Drug Resistant TB cases in 5 Reference Centers - Brazil
From: Outcomes from patients with presumed drug resistant tuberculosis in five reference centers in Brazil
Resistance | Isolates from New cases (n = 87) | Isolates from retreatment cases (n = 23) | ||
|---|---|---|---|---|
N | % (95% CI) | N | % (95% CI) | |
Fully susceptible | 48 | 55.2(44.7–65.2) | 11 | 50.0(30.7–69.3) |
Any resistancea | ||||
 INH | 35 | 40.2(30.5–50.7) | 10 | 45.4(26.9–63.4) |
 RMP | 24 | 27.6(19.3–37.8) | 7 | 31.8(16.2–52.8) |
 EMB | 16 | 18.4(11.5–27.9) | 1 | 4.5(0.1–29.0) |
 SM | 14 | 16.1(9.7–25.3) | 4 | 18.9(6.7–39.1) |
 PZA | 6 | 6.9(2.9–14.5) | 1 | 4.5(0.1–29.0) |
Multidrug resistance | 22 | 25.3(17.3–35.4) | 6 | 27.3(12.9–48.4) |
 RMP + INH | 7 | 8.1(3.7–15.5) | 3 | 13.6(3.9–34.2) |
 RMP + INH + EMB | 2 | 2.3(0.1–6.7) | − | − |
 RMP + INH + SM | 1 | 1.2(0.05–6.7) | 2 | 9.1(1.3–29.0) |
 RMP + INH + EMB + SM | 7 | 8.1(3.7–15.5) | − | − |
Other forms of Resistance | 5 | 5.7(2.2–13.1) | 1 | 4.5(0.1–29.0) |
 INH only | 6 | 6.9(2.9–14.5) | 2 | 9.1(1.3–29.0) |
 RMP only | 1 | 1.2(0.05–6.7) | − | − |
 SM only | 1 | 1.2(0.05–6.7) | 1 | 4.5(0.1–29.0) |
 EMB only | 1 | 1.2(0.05–6.7) | − | − |
 PZA only | 1 | 1.2(0.05–6.7) | − | − |
Number of drugs to which patients were resistant | ||||
 0 | 48 | 55.2(44.7–65.2) | 11 | 50.0(30.7–69.3) |
 1 | 10 | 11.5(6.2–20.1) | 3 | 13.6(3.9–34.2) |
 2 | 13 | 14.9(8.8–24.0) | 4 | 18.9(6.7–39.1) |
 3 | 5 | 5.7(2.2–13.1) | 4 | 18.9(6.7–39.1) |
 4 | 11 | 12.6(7.0–21.4) | 1 | 50.0(30.7–69.3) |