Table 2 Characteristics associated with tuberculosis infection status in child contacts of drug-susceptible tuberculosis and multidrug-resistant tuberculosis
Total | Infected N (%) | OR (95%CI) | AOR (95% CI) | |
|---|---|---|---|---|
Child factors | ||||
Age < 2 years | 203 | 64 (31.5%) | ref | ref |
Age ≥ 2 years | 335 | 144 (43%) | 1.64 (1.13, 2.36) | 1.61 (1.09, 2.37) |
Female | 259 | 96 (37.1%) | ref | ref |
Male | 278 | 112 (40.3%) | 1.15 (0.81, 1.62) | 1.02 (0.70, 1.47) |
Mixed race / other ethnicity | 390 | 161 (41.3%) | ref | ref |
Black African ethnicity | 148 | 47 (31.8%) | 0.66 (0.44, 0.99) | 0.54 (0.33, 0.88) |
HIV-negative | 518 | 202 (39%) | ref | ref |
HIV-positive | 9 | 3 (33.3%) | 0.78 (0.19, 3.16) | 0.66 (0.15, 2.94) |
No BCG scar /no vaccination documented | 45 | 16 (35.6%) | ref | ref |
BCG scar/vaccination documented | 487 | 191 (39.2%) | 1.17 (0.62, 2.21) | 1.62 (0.80, 3.29) |
No prior tuberculosis treatment (disease) | 509 | 189 (37.1%) | ref | ref |
Prior tuberculosis treatment (disease) | 29 | 19 (65.5%) | 3.22 (1.47, 7.06) | 2.36 (1.03, 5.39) |
Weight for age (z-score) ≥ −2 | 482 | 186 (38.6%) | ref | ref |
Weight for age (z-score) < −2 | 54 | 21 (38.9%) | 1.01 (0.57, 1.80) | 1.04 (0.56, 1.92) |
Sleeps in different room to TB source case | 348 | 132 (37.9%) | ref | ref |
Sleeps in same room as TB source case | 113 | 40 (35.4%) | 0.90 (0.58, 1.40) | 0.85 (0.53, 1.36) |
Sleeps in same bed as TB source case | 77 | 36 (46.8%) | 1.44 (0.87, 2.36) | 1.05 (0.60, 1.82) |
Adult source case/household factors | ||||
DS-TB source case | 312 | 107 (34.3%) | ref | ref |
MDR-TB source case | 226 | 101 (44.7%) | 1.55 (1.09, 2.20) | 2.05 (1.34, 3.12) |
No household tobacco smoke exposure | 144 | 50 (34.7%) | ref | ref |
Household tobacco smoke exposure | 394 | 158 (40.1%) | 1.26 (0.85, 1.87) | 1.22 (0.76, 1.94) |
Socioeconomic index ≥ 5/11 | 419 | 165 (39.4%) | ref | ref |
Socioeconomic index <5/11 | 119 | 43 (36.1%) | 0.87 (0.57, 1.33) | 0.79 (0.51, 1.25) |