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Table 6 Stratified analysis of distribution of rs12998782, rs1194182 and rs10499859 alleles, and genotype frequencies in PTB patients and healthy controls according to the levels of albumin

From: Evaluation of the relationship between MARCO and CD36 single-nucleotide polymorphisms and susceptibility to pulmonary tuberculosis in a Chinese Han population

 

ALB < 40(g/L)

ALB > 40(g/L)

Patients

Controls

OR

χ2

95% CI

P

Patients

Controls

OR

χ2

95% CI

P

(n = 202)

(n = 216)

(n = 202)

(n = 216)

MARCO

rs12998782

Genotype

 CC

50

11

    

64

120

    

 CT

28

5

1.232

0.126

0.389–3.906

0.723

36

72

0.952

0.036

0.576–1.575

0.849

 TT

7

0

12

8

2.813

4.907

1.094–7.233

0.027*

 CC + CT

78

16

    

100

192

    

 TT

7

0

12

8

2.88

5.395

1.140–7.275

0.02*

Allele

 C

78

16

    

100

192

    

 T

92

16

1.179

0.194

0.554–2.511

0.688

124

208

1.145

0.65

0.824–1.59

0.42

CD36

rs1194182

Genotype

 CC

18

3

    

26

49

    

 CG

53

8

1.104

<0.0001

0.246–4.617

1

70

92

1.434

1.553

0.812–2.531

0.213

 GG

15

5

0.5

0.222

0.102–2.444

0.638

16

61

0.494

3.664

0.239–1.023

0.056

 CC + CG

71

11

    

96

141

    

 GG

15

5

0.465

0.873

0.141–1.535

0.35

16

61

0.385

9.857

0.21–0.708

0.002*

Allele

 C

89

14

    

122

190

    

 G

83

18

0.725

0.69

0.339–1.551

0.406

102

214

0.742

3.186

0.535–1.03

0.074

rs10499859

Genotype

 AA

35

5

    

42

52

    

 AG

42

7

0.857

0.06

0.25–2.939

0.806

64

95

0.834

0.476

0.498–1.397

0.49

 GG

8

4

0.286

2.799

0.062–1.31

0.094

6

53

0.14

20.052

0.055–0.385

<0.001*

 AA + AG

77

12

    

106

147

    

 GG

8

4

0.312

3.125

0.081–1.197

0.077

6

53

0.157

20.929

0.065–0.379

<0.001*

Allele

 A

112

17

    

148

199

    

 G

58

15

0.587

1.899

0.274–1.259

0.168

76

201

0.508

15.495

0.362–0.714

<0.001*

  1. OR odds ratio, 95% CI 95% confidence interval
  2. *P< 0.05 indicates statistical significance