Antiretroviral therapy initiation within seven days of enrolment: outcomes and time to undetectable viral load among children at an urban HIV clinic in Uganda

Table 5 Multivariate analysis results showing predictors for undetectable viral load

Variable	N = 367		%	Unadj. HR	95% CI	SHR^a	95% CI	P
Age category	0–5	269	73.30	1.0 (ref)
	6–15	83	22.62	1.34	0.90–2.03	0.49	0.17–1.38	0.174
	15–18	15	4.09	2.32	0.84–6.40	0.37	0.06–2.15	0.270
ART initiation	Beyond 7 days after enrolment	187	50.95	1.0 (ref)
ART initiation	Within 7 days after enrolment	180	49.05	1.88	1.35–2.62	2.02	1.24–3.28	0.005*
Baseline CD4 count (cells/ μl)	<500	109	29.70	1.0 (ref)
Baseline CD4 count (cells/ μl)	> = 500	258	70.30	0.92	0.62–1.38	1.36	0.80–2.32	0.252
Adherence to ART	Good adherence on > = 3 consecutive visits	110	29.97	1.0 (ref)
Adherence to ART	Inconsistent adherence	257	70.03	0.67	0.48–0.93	0.44	0.28–0.67	0.001*
ART regimen	NVP based	143	38.96	1.0 (ref)
	EFV based	72	19.62	2.03	1.17–3.51	1.33	0.68–2.60	0.407
	PI based	135	36.78	1.38	0.97–1.96	1.31	0.87–1.98	0.201
	Triple RTI regimen	17	4.63	0.51	0.18–1.46	0.39	0.09–1.63	0.196
Baseline Viral load (copies/ml)	>100,000	265	72.21	1.0 (ref)
Baseline Viral load (copies/ml)	<100,000	102	27.79	1.44	1.03–2.03	0.84	0.55–1.27	0.411
Baseline WHO stage	Stage III or IV	231	62.94	1.0 (ref)
Baseline WHO stage	Stage I or II	136	37.06	1.55	1.11–2.18	1.59	1.06–2.28	0.024*
Baseline weight				1.02	1.01–1.03	1.04	1.01–1.07	0.019*

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