Table 3 Baseline characteristics of included smear-negative presumptive TB patients who had a negative Xpert® MTB/RIF result by actual empirical TB treatment initiation
Characteristic | Post-XP empirical Rx | No post-XP empirical Rx | Total | P-value | |
|---|---|---|---|---|---|
Total (n [%]) | 22 | 130 | 152 | ||
Age (mean [SD]) | 36 (12) | 41 (11) | 40 (10) | 0.04 | |
Female sex (n [%]) | 13 (59.1) | 71 (54.6) | 84 (55.3) | 0.70 | |
CD4 count (median [IQR])* | 239 (139, 329) | 289 (133, 456) | 283 (133, 441) | 0.25 | |
ART at presentation | 12 (54.5) | 69 (53.1) | 81 (53.3) | 0.90 | |
Prior TB treatment (n [%]) | 1 (4.5) | 25 (19.2) | 26 (17.1) | 0.09 | |
Symptomatology at presentation (n [%]) | Cough | 21 (95.5) | 129 (99.2) | 150 (98.7) | 0.15 |
Fever | 16 (72.7) | 91 (70) | 107 (70.4) | 0.80 | |
Night sweats | 11 (50) | 61 (46.9) | 72 (47.4) | 0.79 | |
Weight loss | 10 (45.5) | 38 (29.2) | 48 (31.6) | 0.13 | |
Anorexia | 13 (59.1) | 55 (42.3) | 68 (44.7) | 0.14 | |
Chest pain | 8 (36.4) | 42 (32.3) | 50 (32.9) | 0.70 |