Table 2 Baseline characteristics of smear-negative presumptive TB patients who received an Xpert® MTB/RIF by whether the clinician would have treated them without access to the Xpert result or not
Characteristic | No pre-XP empirical diagnosis | Pre-XP empirical diagnosis | Missing response | Total | P-value | |
|---|---|---|---|---|---|---|
Total (n [%]) | 142 | 29 | 4 | 175 | ||
Age (mean[SD]) | 40 (11) | 39 (9) | 47 (11) | 40 (11) | 0.52 | |
Female sex (n [%]) | 80 (56.3) | 16 (55.2) | 3 (75) | 99 (56.6) | 0.75 | |
CD4 count (median [IQR])* | 280 (189, 483) | 238 (132, 343) | 403 (390, 983) | 275 (179, 478) | 0.66 | |
ART at TB treatment initiation (n [%]) | 72 (50.7) | 16 (55.2) | 1 (25) | 89 (50.9) | 0.53 | |
Prior TB treatment (n [%]) | 23 (16.2) | 6 (20.7) | 0 (0) | 29 (16.6) | 0.55 | |
Symptomatology at presentation (n [%]) | Cough | 140 (98.6) | 29 (100) | 4 (100) | 173 (98.9) | 0.79 |
Fever | 101 (71.1) | 19 (65.5) | 4 (100) | 124 (70.9) | 0.36 | |
Night sweats | 72 (50.7) | 13 (44.8) | 3 (75) | 88 (50.3) | 0.51 | |
Weight loss | 48 (33.8) | 14 (48.3) | 1 (25) | 63 (36) | 0.3 | |
Anorexia | 67 (47.2) | 14 (48.3) | 3 (75) | 84 (48) | 0.55 | |
Chest pain | 46 (32.4) | 10 (34.5) | 1 (25) | 57 (32.6) | 0.93 |