Table 4 Schematic description of clinical outcomes according to MIC, genotype, age, Charlson comorbidity index (CCI), presence of concomitant bacteremia and septic shock in cefepime, piperacillin/tazobactam and ertapenem groups
Case | MIC (μg/mL) | ESBLs genotype | CCI | Bacteremia | Septic shock | Clinical outcome |
|---|---|---|---|---|---|---|
A. Cefepime (NÂ =Â 6) | ||||||
 Patient 1 | 2 | CTX-M-14 | 5 | No | No | Success |
 Patient 2 | 2 | CTX-M-14 | 3 | No | No | Success |
 Patient 3 | 1 | CTX-M-14 | 4 | No | No | Failure |
 Patient 4 | 2 | CTX-M-14 | 6 | No | No | Failure |
 Patient 5 | 1 | SHV-12 | 5 | No | Yes | Failure and expired |
 Patient 6 | 2 | CTX-M-14 | 5 | No | Yes | Failure and expired |
B. Piperacillin/tazobactam (NÂ =Â 33) | ||||||
 Patient 1 | 4 | CTX-M-14 | 6 | No | No | Success |
 Patient 2 | 4 | CTX-M-15 | 5 | No | Yes | Success |
 Patient 3 | 4 | CTX-M-15 | 0 | No | No | Success |
 Patient 4 | 4 | CTX-M-15 | 1 | No | No | Success |
 Patient 5 | 4 | CTX-M-27 | 9 | No | No | Success |
 Patient 6 | 4 | CTX-M-27 | 9 | No | No | Success |
 Patient 7 | 4 | CTX-M-27 | 9 | No | No | Success |
 Patient 8 | 8 | CTX-M-14 | 3 | Yes | Yes | Success |
 Patient 9 | 8 | CTX-M-14 | 1 | No | No | Success |
 Patient 10 | 16 | CTX-M-1 | 4 | No | No | Success |
 Patient 11 | 16 | CTX-M-3 | 2 | No | Yes | Success |
 Patient 12 | 16 | CTX-M-14 | 3 | No | No | Success |
 Patient 13 | 16 | CTX-M-14 | 3 | Yes | Yes | Success |
 Patient 14 | 16 | CTX-M-15 | 1 | No | Yes | Success |
 Patient 15 | 16 | CTX-M-15 | 4 | No | No | Success |
 Patient 16 | 16 | CTX-M-27 | 0 | No | No | Success |
 Patient 17 | 16 | CTX-M-15 | 3 | No | No | Success |
 Patient 18 | 16 | CTX-M-14 | 5 | No | No | Success |
 Patient 19 | 16 | CTX-M-14 | 7 | No | No | Success |
 Patient 20 | 16 | CTX-M-14 | 1 | Yes | No | Success |
 Patient 21 | 16 | CTX-M-14 | 8 | No | No | Success |
 Patient 22 | 16 | Not tested | 5 | No | No | Success |
 Patient 23 | 16 | Not tested | 2 | No | Yes | Success |
 Patient 24 | 16 | Not tested | 7 | No | No | Success |
 Patient 25 | 16 | Not tested | 3 | No | No | Success |
 Patient 26 | 16 | Not tested | 7 | No | No | Success |
 Patient 27 | 16 | Not tested | 8 | No | No | Success |
 Patient 28 | 16 | Not tested | 5 | No | No | Success |
 Patient 29 | 16 | Not tested | 5 | No | No | Success |
 Patient 30 | 16 | Not tested | 3 | Yes | No | Success |
 Patient 31 | 16 | Not tested | 7 | Yes | Yes | Success |
 Patient 32 | 16 | CTX-M-15 | 9 | Yes | Yes | Failure and expired |
 Patient 33 | 16 | CTX-M-27 | 10 | No | Yes | Failure and expired |
C. Ertapenem (NÂ =Â 33) | ||||||
 Patient 1 | 0.5 | CTX-M-15 | 0 | No | No | Success |
 Patient 2 | 0.5 | CTX-M-27 | 0 | No | No | Success |
 Patient 3 | 0.5 | CTX-M-14 | 1 | No | No | Success |
 Patient 4 | 0.5 | CTX-M-15 | 1 | No | No | Success |
 Patient 5 | 0.5 | CTX-M-14 | 1 | Yes | No | Success |
 Patient 6 | 0.5 | CTX-M-15 | 1 | No | Yes | Success |
 Patient 7 | 0.5 | CTX-M-3 | 2 | No | Yes | Success |
 Patient 8 | 0.5 | CTX-M-14 | 2 | Yes | Yes | Success |
 Patient 9 | 0.5 | CTX-M-14 | 3 | No | No | Success |
 Patient 10 | 0.5 | CTX-M-15 | 3 | No | No | Success |
 Patient 11 | 0.5 | CTX-M-15 | 3 | No | No | Success |
 Patient 12 | 0.5 | CTX-M-14 | 3 | Yes | No | Success |
 Patient 13 | 0.5 | CTX-M-14 | 3 | Yes | Yes | Success |
 Patient 14 | 0.5 | CTX-M-14 | 3 | Yes | Yes | Success |
 Patient 15 | 0.5 | CTX-M-1 | 4 | No | No | Success |
 Patient 16 | 0.5 | CTX-M-15 | 4 | No | No | Success |
 Patient 17 | 0.5 | CTX-M-14 | 5 | No | No | Success |
 Patient 18 | 0.5 | CTX-M-14 | 5 | No | No | Success |
 Patient 19 | 0.5 | CTX-M-15 | 5 | No | No | Success |
 Patient 20 | 0.5 | CTX-M-14 | 5 | Yes | No | Success |
 Patient 23 | 0.5 | CTX-M-15 | 5 | No | Yes | Success |
 Patient 21 | 0.5 | CTX-M-14 | 6 | Yes | No | Success |
 Patient 22 | 0.5 | CTX-M-14 | 7 | No | No | Success |
 Patient 24 | 0.5 | CTX-M-14 | 7 | No | No | Success |
 Patient 25 | 0.5 | CTX-M-14 | 7 | No | No | Success |
 Patient 26 | 0.5 | CTX-M-14 | 8 | No | No | Success |
 Patient 27 | 0.5 | CTX-M-14 | 8 | No | No | Success |
 Patient 28 | 0.5 | CTX-M-27 | 9 | No | No | Success |
 Patient 29 | 0.5 | CTX-M-27 | 9 | No | No | Success |
 Patient 30 | 0.5 | CTX-M-27 | 9 | No | No | Success |
 Patient 31 | 0.5 | CTX-M-27 | 10 | No | No | Success |
 Patient 32 | 0.5 | CTX-M-14 | 9 | Yes | Yes | Failure and expired |
 Patient 33 | 0.5 | CTX-M-15 | 7 | Yes | Yes | Failure and expired |