Table 2 Distribution of different genotypes at ABCC2 rs 717,620 (−24 C > T), ABCC4 rs1751034 (3463 A > G) and ABCC10 rs2125739 (T > C) in patients treated with tenofovir with or without KTD
Overall population N = 158 | Patients with KTD n = 42 | Patients without KTD n = 116 | p* | ||||
|---|---|---|---|---|---|---|---|
ABCC2 -24 C > T, rs717620 (%) | |||||||
C/C | 104 | 65.8% | 25 | 59.5% | 79 | 68.1% | 0.503 |
C/T | 52 | 32.9% | 16 | 38.1% | 36 | 31.0% | |
T/T | 2 | 1.3% | 1 | 2.4% | 1 | 0.9% | |
ABCC4 3463 A > G, rs1751034 (%) | |||||||
A/A | 92 | 58.2% | 27 | 64.3% | 65 | 56.0% | 0.010 |
A/G | 56 | 35.5% | 9 | 21.4% | 47 | 40.5% | |
G/G | 10 | 6.3% | 6 | 14.3% | 4 | 3.5% | |
ABCC10 rs2125739, T > C (%) | |||||||
T/T | 80 | 50.6% | 19 | 45.2% | 61 | 52.6% | 0.394 |
T/C | 66 | 41.8% | 21 | 50.0% | 45 | 38.8% | |
C/C | 12 | 7.6% | 2 | 4.8% | 10 | 8.6% | |