Table 1 Univariate analysis of risk factors associated with treatment delay in TBM patients

N

84

77

161

Age (years)

28.3 ± 16.9

34.1 ± 17.2

31.1 ± 17.2

Sex (male)

48

40

88

Time during hospitalization (days)

56.6 ± 44.6

64.6 ± 47.1

60.4 ± 45.9

Fees ($)

78,721 ± 71,922

98,186 ± 108,770

88,030 ± 91,645

Previous anti-TB therapy

5

14

19

Smoking habit (pack-years)

2.82 ± 9.10

3.36 ± 11.9

3.08 ± 10.50

Contact history of TB

10

8

18

No. of Healthcare visits

2.3 ± 0.9

2.8 ± 1.3

2.5 ± 1.1

 Pulmonary TB

54

55

109

 Extrapulmonary TB

23

25

48

 Rheumatic diseases

3

5

8

 Diabetes mellinus

3

8

11

 Milliary TB

22

29

51

 Recurrent TB

3

9

12

 Fever

68

48

116

 Headache

63

27

90

 Vomitting

23

8

31

 Cough

10

20

30

 Hydrocephalus

13

5

18

 Abnormalty in brain CT

37

27

64

 WBC (10⁹/L)

207 ± 210

187 ± 183

198 ± 198

 Mononuclear cells (%)

64 ± 28

54 ± 28

59 ± 29

 Polynuclear cells (%)

36 ± 29

46 ± 28

41 ± 28

 Glucose (mmol/L)

1.96 ± 1.21

2.26 ± 1.81

2.11 ± 1.53

 Tryptophan (+)

59

49

108

 Lactate (mmol/L)

6.75 ± 2.37

6.40 ± 2.43

6.58 ± 2.39

 AST (U/L)

18.7 ± 16.5

17.8 ± 10.5

18.3 ± 13.9

 LDH (U/L)

136 ± 209

120 ± 138

129 ± 178

 CSF-PR (mg/L)

1323 ± 649

1456 ± 758

1387 ± 704

 α-HBDH (U/L)

131 ± 402

70 ± 73

102 ± 296

 Chloride (mmol/L)

108 ± 8

111 ± 8

109 ± 8

 ADA (U/L)

8.1 ± 8.1

8.5 ± 6.4

8.3 ± 7.3

 CSF/Serum glucose

0.32 ± 0.18

0.32 ± 0.18

0.32 ± 0.18

Serum glucose (mmol/L)

6.30 ± 1.54

7.07 ± 3.27

6.66 ± 2.53