Table 3 Performance characteristics of Genotype MTBDRplus VER 2.0 LPA for detection RMP and INH resistance and MDR-TB in smear negative and culture positive direct sample, 2015
Detection of drug resistance | MGIT R | MGIT S | LPA R | LPA S | Sensitivity% | Specificity% | PPV% | NPV% |
|---|---|---|---|---|---|---|---|---|
(95%* CI) | (95%* CI) | (95%* CI) | (95%* CI) | |||||
*RMP | 3 | 11 | 7 | 7 | 100 (29.2–100) | 63.6 (30.8–89.1) | 42.9 (9.9–81.6) | 100 (59–100) |
*INH | 5 | 9 | 3 | 11 | 60 (14.7–94.7) | 100 (66.4–100) | 100 (29.2–100) | 81.8 (48.2–97.7) |
*MDR-TB (RMP&INH) | 2 | 5 | 2 | 5 | 100 (15.8–100) | 100 (47.8–100) | 100 (15.8–100) | 100 (47.8–100) |