Table 3 Logistic regression analysis of 10-year CVD risk ≥10%, by FRS or ASCVD risk score
From: Cardiovascular disease risk among Chinese antiretroviral-naïve adults with advanced HIV disease
Variable | FRS ≥ 10% | ASCVD ≥ 10% | ||
|---|---|---|---|---|
Crude OR (95% CI) | Adjusted ORa (95% CI) | Crude OR (95% CI) | Adjusted ORa (95% CI) | |
Age years | 1.28 (1.21, 1.35) # | 1.42 (1.27, 1.59) # | 1.35 (1.23, 1.49) # | 1.80 (1.28, 2.53) $ |
Female | NA | -- | NA | -- |
Current smoking | 6.88 (3.62, 13.09) # | 61.70 (11.35, 335.57) # | 11.63 (4.43, 30.56) # | 334.16 (8.25, 13,531.31) $ |
BMI | 1.07 (0.97, 1.18) | -- | 0.93 (0.79 1.09) | -- |
Hypertension | 3.99 (1.94, 8.23) # | 2.26 (0.54, 9.39) | 2.16 (0.84, 5.56) † | 2.82 (0.32, 25.29) |
Diabetes | 7.45 (3.41, 16.27) # | 1.33 (0.20, 8.85) | 10.79 (4.18, 27.84) # | 10.58 (0.60, 185.97) |
Dyslipidemia | 2.33 (1.20, 4.51) + | 2.44 (0.67, 8.85) | 1.36 (0.58, 3.18) | -- |
Route of transmission | ||||
MSM | Reference | Reference | Reference | |
Heterosexual | 2.43 (1.17, 5.05) + | 0.24 (0.04, 1.31) | 1.31 (0.46, 3.71) | -- |
Blood | 1.49 (0.32, 7.00) | NA | 0.75 (0.08,7.03) | -- |
Other/unknown | 1.54 (0.41, 5.75) | 0.17 (0.02, 1.96) | 0.85 (0.15 4.73) | -- |
Years since HIV diagnosis | 0.90 (0.71, 1.14) | -- | 0.53 (0.27, 1.05) | -- |
CD4+ count cells/ mm3 | ||||
< 200 | 1.71 (0.63, 4.64) | -- | 1.17 (0.31, 4.47) | -- |
200–349 | 1.50 (0.55, 4.08) | -- | 1.47 (0.39, 5.55) | -- |
> 350 | Reference | Reference | Reference | Reference |
Viral load log10 copies/ml | 1.67 (1.02, 2.73) + | 0. 80 (0.38, 1.71) | 1.84 (0.97, 3.49) † | 1.93 (0.54, 6.86) |