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Table 3 Logistic regression analysis of 10-year CVD risk ≥10%, by FRS or ASCVD risk score

From: Cardiovascular disease risk among Chinese antiretroviral-naïve adults with advanced HIV disease

Variable FRS ≥ 10% ASCVD ≥ 10%
Crude OR
(95% CI)
Adjusted ORa
(95% CI)
Crude OR
(95% CI)
Adjusted ORa
(95% CI)
Age years 1.28 (1.21, 1.35) # 1.42 (1.27, 1.59) # 1.35 (1.23, 1.49) # 1.80 (1.28, 2.53) $
Female NA -- NA --
Current smoking 6.88 (3.62, 13.09) # 61.70 (11.35, 335.57) # 11.63 (4.43, 30.56) # 334.16 (8.25, 13,531.31) $
BMI 1.07 (0.97, 1.18) -- 0.93 (0.79 1.09) --
Hypertension 3.99 (1.94, 8.23) # 2.26 (0.54, 9.39) 2.16 (0.84, 5.56) 2.82 (0.32, 25.29)
Diabetes 7.45 (3.41, 16.27) # 1.33 (0.20, 8.85) 10.79 (4.18, 27.84) # 10.58 (0.60, 185.97)
Dyslipidemia 2.33 (1.20, 4.51) + 2.44 (0.67, 8.85) 1.36 (0.58, 3.18) --
Route of transmission
 MSM Reference Reference Reference  
 Heterosexual 2.43 (1.17, 5.05) + 0.24 (0.04, 1.31) 1.31 (0.46, 3.71) --
 Blood 1.49 (0.32, 7.00) NA 0.75 (0.08,7.03) --
 Other/unknown 1.54 (0.41, 5.75) 0.17 (0.02, 1.96) 0.85 (0.15 4.73) --
Years since HIV diagnosis 0.90 (0.71, 1.14) -- 0.53 (0.27, 1.05) --
CD4+ count cells/ mm3
  < 200 1.71 (0.63, 4.64) -- 1.17 (0.31, 4.47) --
 200–349 1.50 (0.55, 4.08) -- 1.47 (0.39, 5.55) --
  > 350 Reference Reference Reference Reference
Viral load log10 copies/ml 1.67 (1.02, 2.73) + 0. 80 (0.38, 1.71) 1.84 (0.97, 3.49) 1.93 (0.54, 6.86)
  1. *Factors with p < 0.2 in the univariate analyses were included in multivariable regression. OR: Odds ratio; CI: Confidence interval; BMI: body mass index; MSM: Men who have sex with men; FRS, the Framingham Risk Score; ASCVD, Atherosclerotic Cardiovascular Disease Risk Score; NA: not applicable
  2. p < 0.2, + p < 0.05, $ p < 0.01, # p < 0.001