Table 1 Demographic and clinical characteristics of study participants, overall and by sex
From: Cardiovascular disease risk among Chinese antiretroviral-naïve adults with advanced HIV disease
Characteristic | All (n = 973) | Male (n = 722) | Female (n = 251) | p-value |
|---|---|---|---|---|
Age years | 36.0 ± 10.2 | 35.1 ± 10.1 | 38.7 ± 10.1 | <0.001 |
Route of transmission | <0.001b | |||
MSM | 382 (39.3%) | 382 (52.9%) | 0 | |
Heterosexual | 466 (47.9%) | 248 (34.3%) | 218 (86.9%) | |
Blood-borne | 51 (5.2%) | 32 (4.4%) | 19 (7.6%) | |
Other/unknown | 74 (7.6%) | 60 (8.3%) | 14 (5.6%) | |
Years since HIV diagnosis | 1.0 ± 1.6 | 0.8 ± 1.3 | 1.6 ± 2.1 | 0.01 |
CD4+ count cells/mm3 (N = 969) | 229 ± 123 | 227 ± 124 | 233 ± 121 | 0.52 |
HIV RNA log10 copies/ml (N = 710) | 4.69 ± 0.70 | 4.74 ± 0.67 | 4.56 ± 0.77 | <0.01 |
Current smoking | 231 (23.7%) | 223 (30.9%) | 8 (3.2%) | <0.001 |
BMI kg/m2 | 21.6 ± 2.9 | 21.5 ± 2.7 | 21.6 ± 3.3 | 0.82 |
Overweight | 94 (9.7%) | 63 (8.7%) | 31 (12.4%) | 0.09 |
Obesity | 10 (1.0%) | 5 (0.7%) | 5 (2.0%) | 0.08 |
Systolic blood pressure mmHg | 115 ± 13 | 116 ± 12 | 113 ± 14 | <0.01 |
Diastolic blood pressure mmHg | 75 ± 9 | 75 ± 9 | 75 ± 10 | 0.79 |
Hypertension | 82 (8.4%) | 56 (7.8%) | 26 (10.4%) | 0.20 |
Blood glucose mmol/l | 5.3 ± 1.0 | 5.3 ± 1.0 | 5.3 ± 1.1 | 0.77 |
Diabetes | 45 (4.6%) | 33 (4.6%) | 12 (4.8%) | 0.89 |
TC mmol/l | 4.1 ± 1.0 | 4.0 ± 0.9 | 4.2 ± 1.1 | <0.01 |
TG mmol/l | 1.5 ± 1.1 | 1.5 ± 1.1 | 1.5 ± 1.0 | 0.21 |
HDL-c mmol/l | 1.2 ± 0.4 | 1.2 ± 0.4 | 1.3 ± 0.4 | <0.001 |
LDL-c mmol/l | 2.3 ± 0.8 | 2.3 ± 0.8 | 2.3 ± 0.9 | 0.95 |
TC >5.2 mmol/l | 104 (10.7%) | 66 (9.1%) | 38 (15.1%) | <0.01 |
TG >1.7 mmol/l | 282 (29.0%) | 215 (29.8%) | 67 (26.7%) | 0.35 |
HDL-c < 1.0 mmol/l | 299 (30.7%) | 249 (34.5%) | 50 (19.9%) | <0.001 |
LDL-c > 4.1 mmol/l | 17 (1.7%) | 9 (1.2%) | 8 (3.2%) | 0.04 |
Dyslipidemia | 503 (51.7%) | 388 (53.7%) | 115 (45.8%) | 0.03 |
Number of CVD risk factorsa | ||||
Only one | 465 (47.8%) | 361 (50.0%) | 104 (41.4%) | 0.019 |
Two or more | 194 (19.9%) | 164 (22.7%) | 30 (12.0%) | <0.001 |