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Table 1 Number of significantly modulated genes in spleen and brain

From: Differential host gene responses from infection with neurovirulent and partially-neurovirulent strains of Venezuelan equine encephalitis virus

 

Spleen

Brain

24 h pi

48 h pi

72 h pi

48 h pi

72 h pi

96 h pi

V3000

 Upregulated

136

255

241

75

57

210

 Downregulated

188

276

245

166

111

169

 Total

324

531

486

241

168

379

V3034

 Upregulated

58

252

210

62

79

71

 Downregulated

31

253

38

92

127

153

 Total

89

505

248

154

206

224

  1. Total RNA extracted from V3000 and V3034 infected spleen and brain was used to perform whole genome microarray as described in methods. Gene’s modulated in all the replicates (n = 3), ≥2.0 fold (i.e., log2 ratio ≥ 1.0 or ≤ −1.0) relative expression level over uninfected controls, and p-value ≤0.05 were considered significant