Table 3 Results of univariable and multivariable binomial regression analysis of predictors of month-two culture non-conversion
From: Predictors of delayed culture conversion among Ugandan patients
Characteristic | Converted, n (%) | Non-converted, n (%) | Unadjusted RR [95% CI] | Adjusted RR [95% CI] |
|---|---|---|---|---|
Age in years, n = 100 | ||||
18–45 | 36 (43.4) | 47 (56.6) | 1.2 [0.70–2.06] | 0.6 [0.32–1.32] |
> 45 | 9 (52.9) | 8 (47.1) | 1.0 | 1.0 |
Gender, n = 100 | ||||
Female | 10 (50.0) | 10 (50.0) | 1.0 | 1.0 |
Male | 35 (43.8) | 45 (56.3) | 1.1 [0.70–1.82] | 1.1 [0.60–2.06] |
Marital status, n = 92 | ||||
Married | 26 (48.2) | 28 (51.9) | 1.0 [0.67–1.61] | |
Separated/Divorced | 2 (25.0) | 6 (75.0) | 1.5 [0.88–2.57] | |
Single/widowed | 15 (50.0) | 15 (50.0) | 1.0 | |
Occupation, n = 92 | ||||
Peasant | 11 (68.8) | 5 (31.3) | 0.9 [0.29–3.04] | 0.8 [0.26–2.65] |
Professional | 6 (66.7) | 3 (33.3) | 1.0 | 1.0 |
Social service | 3 (16.7) | 15 (83.3) | 2.5 [0.97–6.44] | 3.0 [1.10–8.19] |
Unskilled manual | 17 (46.0) | 20 (54.1) | 1.6 [0.61–4.28] | a1.5 [0.56–3.78] |
Student | 3 (50.0) | 3 (50.0) | 1.5 [0.44–5.09] | 2.1 [0.61–7.11] |
Business | 3 (50.0) | 3 (50.0) | 1.5 [0.44–5.09] | 1.3 [0.40–4.36] |
District of residence, N = 100 | ||||
Bushenyi | 5 (55.6) | 4 (44.4) | 1.0 | |
Isingiro | 8 (38.1) | 13 (61.9) | 1.4 [0.62–3.11] | |
Mbarara | 32 (45.7) | 38 (54.3) | 1.2 [0.57–2.62] | |
Current Smoker, n = 89 | 15 (42.9) | 20 (57.1) | 1.1 [0.74–1.62] | |
TB treatment regimen, n = 100 | ||||
Standard regimen | 17 (50.0) | 17 (50.0) | 1.0 | 1.0 |
Regimen 1 | 13 (40.6) | 19 (59.4) | 1.5 [0.55–3.87] | 0.8 [0.45–1.34] |
Regimen 2 | 15 (44.1) | 19 (55.9) | 1.3 [0.49–3.29] | 1.1 [0.69–1.84] |
Body mass index in kg/m2, n = 99 | ||||
18.5 and above | 25 (45.5) | 30 (54.6) | 1.0 | |
< 18.5 | 20 (45.5) | 24 (54.6) | 1.0 [0.70–1.44] | |
Colony density at baseline, n = 98 | ||||
1+ | 2 (50.0) | 2 (50.0) | 1.0 | 1.0 |
2+ | 8 (57.1) | 6 (42.9) | 0.9 [0.27–2.71] | 0.5 [0.12–2.01] |
3+ | 23 (41.1) | 33 (58.9) | 1.2 [0.43–3.22] | 0.5 [0.11–1.82] |
4+ | 11 (45.8) | 13 (54.2) | 1.1 [0.38–3.09] | 0.4 [0.09–1.44] |
Time-to-detection (TDD) of MTB on MGIT at baseline | ||||
Less than 14 days | 24 (36.9) | 41 (63.1) | 1.6 [0.98–2.54] | 2.1 [1.18–3.93]b |
14 days and above | 18 (60.0) | 12 (40.0) | 1.0 | 1.0 |
Hemoglobin levels, n = 100 | ||||
Normal | 28 (40.0) | 42 (60.0) | 1.0 | |
Low | 17 (56.7) | 13 (43.3) | 0.7 [0.46–1.13] | |
Missed atleast a dose in first 2 months, n = 100 | 3 (23.1) | 10 (76.9) | 1.5 [1.04–2.13] | |