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Table 3 Results of univariable and multivariable binomial regression analysis of predictors of month-two culture non-conversion

From: Predictors of delayed culture conversion among Ugandan patients

Characteristic Converted,
n (%)
Non-converted,
n (%)
Unadjusted
RR [95% CI]
Adjusted
RR [95% CI]
Age in years, n = 100
 18–45 36 (43.4) 47 (56.6) 1.2 [0.70–2.06] 0.6 [0.32–1.32]
  > 45 9 (52.9) 8 (47.1) 1.0 1.0
Gender, n = 100
 Female 10 (50.0) 10 (50.0) 1.0 1.0
 Male 35 (43.8) 45 (56.3) 1.1 [0.70–1.82] 1.1 [0.60–2.06]
Marital status, n = 92
 Married 26 (48.2) 28 (51.9) 1.0 [0.67–1.61]  
 Separated/Divorced 2 (25.0) 6 (75.0) 1.5 [0.88–2.57]  
 Single/widowed 15 (50.0) 15 (50.0) 1.0  
Occupation, n = 92
 Peasant 11 (68.8) 5 (31.3) 0.9 [0.29–3.04] 0.8 [0.26–2.65]
 Professional 6 (66.7) 3 (33.3) 1.0 1.0
 Social service 3 (16.7) 15 (83.3) 2.5 [0.97–6.44] 3.0 [1.10–8.19]
 Unskilled manual 17 (46.0) 20 (54.1) 1.6 [0.61–4.28] a1.5 [0.56–3.78]
 Student 3 (50.0) 3 (50.0) 1.5 [0.44–5.09] 2.1 [0.61–7.11]
 Business 3 (50.0) 3 (50.0) 1.5 [0.44–5.09] 1.3 [0.40–4.36]
District of residence, N = 100
 Bushenyi 5 (55.6) 4 (44.4) 1.0  
 Isingiro 8 (38.1) 13 (61.9) 1.4 [0.62–3.11]  
 Mbarara 32 (45.7) 38 (54.3) 1.2 [0.57–2.62]  
Current Smoker, n = 89 15 (42.9) 20 (57.1) 1.1 [0.74–1.62]  
TB treatment regimen, n = 100  
 Standard regimen 17 (50.0) 17 (50.0) 1.0 1.0
 Regimen 1 13 (40.6) 19 (59.4) 1.5 [0.55–3.87] 0.8 [0.45–1.34]
 Regimen 2 15 (44.1) 19 (55.9) 1.3 [0.49–3.29] 1.1 [0.69–1.84]
Body mass index in kg/m2, n = 99
 18.5 and above 25 (45.5) 30 (54.6) 1.0  
  < 18.5 20 (45.5) 24 (54.6) 1.0 [0.70–1.44]  
Colony density at baseline, n = 98
 1+ 2 (50.0) 2 (50.0) 1.0 1.0
 2+ 8 (57.1) 6 (42.9) 0.9 [0.27–2.71] 0.5 [0.12–2.01]
 3+ 23 (41.1) 33 (58.9) 1.2 [0.43–3.22] 0.5 [0.11–1.82]
 4+ 11 (45.8) 13 (54.2) 1.1 [0.38–3.09] 0.4 [0.09–1.44]
Time-to-detection (TDD) of MTB on MGIT at baseline     
 Less than 14 days 24 (36.9) 41 (63.1) 1.6 [0.98–2.54] 2.1 [1.18–3.93]b
 14 days and above 18 (60.0) 12 (40.0) 1.0 1.0
Hemoglobin levels, n = 100
 Normal 28 (40.0) 42 (60.0) 1.0  
 Low 17 (56.7) 13 (43.3) 0.7 [0.46–1.13]  
Missed atleast a dose in first 2 months, n = 100 3 (23.1) 10 (76.9) 1.5 [1.04–2.13]  
  1. Multivariable model characteristics: N = 87, deviance = 100.63, Binomial model-based goodness of fit, p = 0.0177, Logit model-based goodness of fit, p = 0.5291
  2. RR crude risk ratio, aRR adjusted risk ratio, 95% CI 95% Confidence Interval, LJ Löwenstein-Jensen, MGIT mycobacterium growth indicator tube, NA not applicable, MTB mycobacterium tuberculosis a p = 0.031; b p = 0.013