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Table 3 Factors associated with 1,25-hydroxyvitamin D and 25-hydroxyvitamin D in tuberculosis patients and control subjects

From: Vitamin D and activated vitamin D in tuberculosis in equatorial Malaysia: a prospective clinical study

  25-hydroxyvitamin D   1,25-hydroxyvitamin D  
  Univariable analyses Multivariable analyses Univariable analyses Multivariable analyses
  β coefficient P value β coefficient P value β coefficient P value β coefficient P value
Tuberculosis
 Sex (0 = female, 1 = male) 14.65 <0.001 −12.80 0.007 25.85 0.064 −34.37 0.057
 Age 0.41 0.001 0.32 0.024 −0.98 0.055 −1.83 0.001
 BMI 0.31 0.561 - - −3.59 0.111 - -
 Smoking (0 = no, 1 = yes) 12.91 <0.001 4.84 0.062 5.13 0.711 −7.66 0.468
 Albumin 0.86 0.057 0.46 0.356 −4.14 0.018 −4.52 0.021
 VDBP 0.04 0.023 0.03 0.037 0.00 0.943 0.00 0.514
 X-ray severity score −0.09 0.125 −0.11 0.054 0.97 <0.001 0.68 0.003
Controls
 Sex (0 = female, 1 = male) 13.92 0.001 −8.64 0.077 1.00 0.744 −35.40 0.23
 Age 0.42 0.012 0.04 0.045 −1.14 0.062 −1.69 0.08
 BMI −0.21 0.637 - - −1.40 0.453 - -
 Smoking (0 = no, 1 = yes) 12.15 0.009 3.19 0.471 1.00 0.497 2.40 0.92
 Albumin 0.57 0.424 0.13 0.858 0.55 0.885 −3.92 0.35
 VDBP 0.03 0.175 0.00 0.778 0.07 0.389 0.00 0.17
  1. P values ≤0.05 shown in bold
  2. Multivariable models include sex, age, smoking, albumin, VDBP and for TB patients, x-ray score
  3. A transformation was applied to achieve a normal distribution for VDBP (square root)