BMC Infectious Diseases

Table 3 Factors associated with 1,25-hydroxyvitamin D and 25-hydroxyvitamin D in tuberculosis patients and control subjects

From: Vitamin D and activated vitamin D in tuberculosis in equatorial Malaysia: a prospective clinical study

	25-hydroxyvitamin D				1,25-hydroxyvitamin D
	Univariable analyses		Multivariable analyses		Univariable analyses		Multivariable analyses
	β coefficient	P value	β coefficient	P value	β coefficient	P value	β coefficient	P value
Tuberculosis
Sex (0 = female, 1 = male)	14.65	<0.001	−12.80	0.007	25.85	0.064	−34.37	0.057
Age	0.41	0.001	0.32	0.024	−0.98	0.055	−1.83	0.001
BMI	0.31	0.561	-	-	−3.59	0.111	-	-
Smoking (0 = no, 1 = yes)	12.91	<0.001	4.84	0.062	5.13	0.711	−7.66	0.468
Albumin	0.86	0.057	0.46	0.356	−4.14	0.018	−4.52	0.021
VDBP	0.04	0.023	0.03	0.037	0.00	0.943	0.00	0.514
X-ray severity score	−0.09	0.125	−0.11	0.054	0.97	<0.001	0.68	0.003
Controls
Sex (0 = female, 1 = male)	13.92	0.001	−8.64	0.077	1.00	0.744	−35.40	0.23
Age	0.42	0.012	0.04	0.045	−1.14	0.062	−1.69	0.08
BMI	−0.21	0.637	-	-	−1.40	0.453	-	-
Smoking (0 = no, 1 = yes)	12.15	0.009	3.19	0.471	1.00	0.497	2.40	0.92
Albumin	0.57	0.424	0.13	0.858	0.55	0.885	−3.92	0.35
VDBP	0.03	0.175	0.00	0.778	0.07	0.389	0.00	0.17

P values ≤0.05 shown in bold
Multivariable models include sex, age, smoking, albumin, VDBP and for TB patients, x-ray score
A transformation was applied to achieve a normal distribution for VDBP (square root)

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