Association of mannose-binding lectin gene polymorphisms with the development of pulmonary tuberculosis in China

BMC Infectious Diseases

Table 2 MBL2 gene polymorphisms in TB patients with different demographic characteristic (n = 112)

Characteristic	Total	−221		P value	exon 1 (codons 54)		P value
Characteristic	Total	Y/Y	Y/X+ X/X	OR (95%CI)	A/A	A/B + B/B	OR (95%CI)
Gender
Male	78	45	33	0.687	59	19	0.135
Female	34	21	13	0.84 (0.37–1.92)	21	13	1.92 (0.81–4.56)
Age
≤ 45	72	37	35	0.03	46	26	0.018
> 45	40	29	11	0.40 (0.17–0.92)	34	6	0.31 (0.11–0.84)
Initial TB
Yes	65	45	20	0.009	52	13	0.018
No	47	21	26	2.78 (1.27–6.07)	28	19	2.71 (1.17–6.30)
Fever
Yes	33	20	13	0.816	25	8	0.512
No	79	46	33	1.10 (0.48–2.53)	55	24	1.36 (0.54–3.45)
Cavity
Yes	45	27	18	0.850	33	12	0.715
No	67	39	28	1.08 (0.50–2.32)	47	20	1.17 (0.50–2.72)
Hemoptysis
Yes	46	24	22	0.225	35	11	0.362
No	66	42	24	0.62 (0.29–1.34)	45	21	1.48 (0.63–3.48)

TB tuberculosis, OR odds ratio, CI confidence interval, P values and ORs with confidence intervals (CIs) shown in bold type are statistically significant

ISSN: 1471-2334