Table 1 Baseline characteristics of the study cohort
Variable | Categories | Empirical Antibiotic Therapy | ||
|---|---|---|---|---|
Appropriate (n = 3778) | Inappropriate (n = 1290) | Unknown (n = 1415) | ||
Age, years | 0–15 | 103 (3)a | 25 (2) | 62 (4) |
16–64 | 1294 (34) | 395 (31) | 504 (36) | |
65–79 | 1279 (34) | 476 (37) | 457 (32) | |
80+ | 1102 (29) | 394 (31) | 392 (28) | |
Gender | Female | 1883 (50) | 539 (42) | 630 (45) |
Male | 1895 (50) | 751 (58) | 785 (55) | |
Charlson comorbidity index score | 0 | 1031 (27) | 305 (24) | 426 (30) |
1–2 | 1421 (38) | 476 (37) | 497 (35) | |
>2 | 1326 (35) | 509 (39) | 492 (35) | |
Origin of infection | Community acquired | 2560 (68) | 681 (53) | 680 (48) |
Nosocomial | 674 (18) | 435 (34) | 285 (20) | |
Healthcare associated | 506 (13) | 150 (12) | 135 (10) | |
Unknown | 38 (1) | 24 (2) | 315 (22) | |
Speciality | Medicine | 2657 (70) | 822 (64) | 910 (64) |
Surgery | 887 (23) | 352 (27) | 373 (26) | |
Paediatrics | 92 (2) | 24 (2) | 52 (4) | |
Intensive-care unit | 133 (4) | 83 (6) | 72 (5) | |
Unknown | 9 (0) | 9 (1) | 8 (1) | |
Group of microorganisms | Monomicrobial Gram-negative | 1444 (38) | 398 (31) | 605 (43) |
Monomicrobial Gram-positive | 2037 (54) | 529 (41) | 557 (39) | |
Monomicrobial anaerobic | 104 (3) | 54 (4) | 97 (7) | |
Fungi | 34 (1) | 98 (8) | 45 (3) | |
Polymicrobial | 159 (4) | 211 (16) | 111 (8) | |
Focus of infection | Urogenital | 1287 (34) | 405 (31) | 224 (16) |
Respiratory | 499 (13) | 75 (6) | 74 (5) | |
Abdominal | 508 (13) | 204 (16) | 199 (14) | |
Miscellaneous | 564 (15) | 145 (11) | 219 (15) | |
Unknown | 920 (24) | 461 (36) | 699 (49) | |