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Table 1 Baseline characteristics of patients initiated on multidrug-resistant tuberculosis treatment in Kyiv Oblast, Ukraine (N = 378)

From: Risk factors for poor multidrug-resistant tuberculosis treatment outcomes in Kyiv Oblast, Ukraine

  Cure and Completed (N = 65) n (%) or median (IQR) Default (N = 115) n (%) or median (IQR) Death (N = 131) n (%) or median (IQR) Failure (N = 37) n (%) or median (IQR) Total (N = 378)a n (%) or median (IQR)
Age 36.3 (30.2–44.9) 40.2 (35.2–49.7) 38.2 (33.1–49.6) 36.7 (31.7–42.8) 38.2 (33.0–48.6)
Male 41 (63.1%) 93 (80.9%) 110 (84.0%) 30 (81.1%) 292 (77.2%)
Previous TB treatmentb 48 (75.0%) 96 (88.1%) 104 (84.6%) 31 (83.8%) 305 (84.5%)
Passive Case Findingc 64 (98.5%) 110 (96.5%) 131 (100.0%) 36 (100.0%) 371 (98.7%)
HIV positived 11 (17.2%) 17 (15.0%) 43 (33.1) 5 (13.5%) 82 (21.7%)
On ART during MDR-TB treatment among HIV positive 10 (90.9%) 12 (70.6%) 25 (58.1%) 1 (20.0%) 51 (62.2%)
Smear positive at baselinee 25 (38.5%) 64 (55.7%) 88 (67.2%) 25 (69.4%) 220 (58.4%)
Alcohol abuse 11 (16.9%) 25 (21.7%) 27 (20.6%) 4 (10.8%) 73 (19.3%)
IVDU 2 (3.1%) 0 (0.0%) 6 (4.6%) 2 (5.4%) 11 (2.9%)
Unemployed 30 (46.2%) 75 (65.2%) 87 (66.4%) 22 (59.5%) 235 (62.2%)
Homeless 0 (0.0%) 4 (3.5%) 7 (5.3%) 1 (2.7%) 13 (3.4%)
Rural Residencef 35 (58.3%) 33 (37.1%) 56 (53.3%) 14 (42.4%) 162 (51.8%)
Medical Worker in TB 1 (1.5%) 0 (0.0%) 0 (0.0%) 0 (0.0%) 2 (0.5%)
Previous Incarceration 2 (3.1%) 4 (3.5%) 7 (5.4%) 1 (2.7%) 15 (4.0%)
Known TB contact 1 (1.5%) 1 (0.9%) 1 (0.8%) 0 (0.0%) 3 (0.8%)
Baseline Gene Xpert Test 15 (23.1%) 34 (29.6%) 39 (29.8%) 9 (24.3%) 111 (29.4%)
Extensively drug-resistant (XDR-TB) 2 (3.1%) 6 (5.2%) 18 (13.7%) 5 (13.5%) 35 (9.3%)
  1. IQR interquartile range, ART anti-retroviral therapy, IVDU intravenous drug use
  2. aTotal N includes patients with unknown outcome and those who transferred out
  3. bMissing observations, N = 17
  4. cMissing observations, N = 2
  5. dMissing observations, N = 6
  6. eMissing observations, N = 1
  7. fMissing observations, N = 65