Norovirus positive (n = 23) | Norovirus negative (n = 266) | p | |
---|---|---|---|
Sociodemographic and background characteristics | |||
Sex | 0.240 | ||
Female | 14/22 (63.6) | 127/257 (49.4) | |
Male | 8/22 (36.3) | 130/257 (50.6) | |
Age | 0.797 | ||
< 1 month | 0 (0.0) | 3/266 (1.1) | |
1–6 months | 2/23 (8.7) | 31/266 (11.7) | |
6–12 months | 10/23 (43.5) | 106/266 (39.8) | |
12–24 months | 9/23 (39.1) | 83/266 (31.2) | |
> 24 months | 2/23 (8.7) | 43/266 (16.2) | |
Number of siblings | 0.867 | ||
0 | 8/21 (38.1) | 69/210 (32.9) | |
1 | 4/21 (19.1) | 53/210 (25.2) | |
2 | 4/21 (19.1) | 48/210 (22.9) | |
3 | 2/21 (9.5) | 17/210 (8.1) | |
≥ 4 | 3/21 (14.3) | 23/210 (11.0) | |
Household electricity | 15/23 (65.2) | 164/258 (63.6) | 0.875 |
Household drinking water source | 0.793 | ||
Communal tap | 12/19 (63.1) | 110/244 (45.1) | |
Piped to yard | 3/19 (15.8) | 39/244 (16.0) | |
Piped into dwelling | 2/19 (10.5) | 36/244 (14.8) | |
Protected public well | 1/19 (5.3) | 21/244 (8.6) | |
River/stream | 0/19 (0.0) | 14/244 (5.7) | |
Other | 1/19 (5.3) | 24/244 (9.8) | |
Household livestock | 3/23 (13.0) | 28/251 (11.2) | 0.784 |
Toilet facility | 0.031 | ||
Flush/pour flush to piped sewer | 1/20 (5.0) | 41/225 (18.2) | |
Flush/pour flush to septic tank | 3/20 (15.0) | 42/225 (18.7) | |
Flush/pour flush to pit latrine | 3/20 (15.0) | 3/225 (1.3) | |
Improved ventilated pit latrine | 1/20 (5.0) | 16/225 (7.1) | |
Pit latrine with slab | 10/20 (50.0) | 78/225 (34.7) | |
Open pit latrine without slab | 2/20 (10.0) | 44/225 (19.6) | |
Hanging toilet/hanging latrine | 0/20 (0.0) | 1/225 (0.4) | |
Child ever diagnosed with HIV/AIDS | 0/18 (0.0) | 1/201 (0.5) | 1.000 |
Number of rotavirus vaccines received | |||
0 doses or unknown | 13/23 (56.5) | 171/266 (64.3) | |
At least 1 dose | 10/23 (43.4) | 95/266 (35.7) | 0.458 |
2 doses | 8/23 (34.8) | 79/266 (30.0) | 0.610 |
Clinical features at presentation | |||
Severity score by category | 0.766 | ||
≤ 10 (mild) | 16/19 (84.2) | 156/183 (85.3) | |
11–14 (moderate) | 3/19 (15.8) | 26/183 (14.2) | |
≥ 15 (severe) | 0/19 (0.0) | 1/183 (0.6) | |
Degree of dehydration on admission | 0.319 | ||
None | 2/23 (8.7) | 57/259 (22.0) | |
Mild | 7/23 (30.4) | 55/259 (21.2) | |
Moderate | 14/23 (60.9) | 136/259 (52.5) | |
Severe | 0/23 (0.0) | 11/259 (4.3) | |
Duration of diarrhea, days | 0.505 | ||
1–4 | 21/22 (95.5) | 203/221 (91.9) | |
5 | 1/22 (4.5) | 6/221 (2.7) | |
≥ 6 | 0/22 (0.0) | 12/221 (5.4) | |
Max stools/day | 0.444 | ||
1–3 | 14/22 (63.6) | 112/217 (51.6) | |
4–5 | 8/22 (36.4) | 90/217 (41.5) | |
≥ 6 | 0/22 (0.0) | 15/217 (6.9) | |
Blood in stool | 0/22 (0.0) | 8/216 (3.7) | 1.000 |
Vomiting | 9/21 (42.9) | 83/221 (37.1) | 0.603 |
Duration of vomiting, days | 0.593 | ||
0 | 12/22 (54.6) | 139/221 (62.9) | |
1 | 1/22 (4.6) | 9/221 (4.1) | |
2 | 5/22 (22.7) | 49/221 (22.2) | |
≥ 3 | 4/22 (18.2) | 24/221 (10.9) | |
Maximum vomiting episodes/day | 0.502 | ||
0 | 12/22 (54.6) | 139/218 (63.8) | |
1 | 0/22 (0.0) | 5/218 (2.3) | |
2–4 | 10/22 (45.5) | 65/218 (29.8) | |
≥ 5 | 0/22 (0.0) | 9/218 (4.1) | |
Abdominal pain | 15/22 (68.2) | 137/205 (66.8) | 0.898 |
Caregiver-reported fever | 10/22 (45.5) | 97/217 (44.7) | 0.946 |
Maximal recorded temperature, °C | 0.877 | ||
< 37.0 | 15/22 (68.2) | 172/245 (70.2) | |
37.1–38.4 | 7/22 (31.8) | 60/245 (24.5) | |
38.5–38.9 | 0/22 (0.0) | 6/245 (2.5) | |
≥ 39.0 | 0/22 (0.0) | 7/245 (2.9) | |
Duration of fever | 2.4 (1.2) | 2.6 (1.3) | 0.605 |
Decreased energy/malaise | 13/21 (61.9) | 147/217 (67.7) | 0.586 |
Excessive crying | 14/22 (63.6) | 96/218 (44.0) | 0.079 |
Admitted to hospital | 3/21 (14.3) | 32/223 (14.4) | 1.000 |
Rotavirus positive | 6/23 (26.1) | 104/263 (39.5) | 0.203 |
30 day follow-up | |||
Status of child | 1.000 | ||
Fully recovered | 10/10 (100.0) | 120/133 (90.20) | |
Partially recovered | 0/10 (0.0) | 6/133 (4.5) | |
Worsening | 0/10 (0.0) | 1/133 (0.8) | |
Recovered but became sick again | 0/10 (0.0) | 6/133 (4.5) |