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Table 1 The clinical profile of the study subjects belonging to two different clinical cohorts of India

From: The PTAP sequence duplication in HIV-1 subtype C Gag p6 in drug-naive subjects of India and South Africa

(A) The YRG CARE cohort, n = 30
Subject ID Year of Diagnosis Enrolment date Age/ Gender Time (months from the date of enrolment) GenBank Accn. No.
PVL CD4 CD8  
M0 M12 M24 M0 M6 M12 M18 M24 M30 M0 M12 M24 gag
T-001 22–05–2002 26–11–2010 28/F 12074 29617 60953 560 569 525 530 645 355 1633 1804 1273 KT152633
T-002 22–01–2002 06–12–2010 34/F 15354 16293 6852 517 855 740 879 565 584 610 762 734 KP890700–11
T-004 15–03–2004 16–12–2010 29/F 33784 36627 112577 553 442 508 359 321 296 >2000 >2000 1910 KT152674–686
T-005 13–12–2003 20–12–2010 26/F 912 x x 770 x x x x x >2000 x x KT152634
T-006 25–08–2008 29–12–2010 28/F 1638 24773 x 527 480 409 547 x x 1513 1199 x KP890712–21
T-007 27–10–2007 30–12–2010 26/F <150 263 722 958 799 1016 886 1311 x 859 992 1380 ­
T-008 17–10–2008 20–01–2011 30/F 34640 172183 x 468 480 484 432 476 415 1158 1083 901 KP890722-38
T-009 24–08–2006 24–01–2011 27/F 14672 76956 24797 695 x 603 x 330 x 1927 1930 928 KP890739-45
T-010 22–02–1996 29–01–2011 39/F <150 <150 <150 641 785 813 NA 525 x 880 1105 679 ­
T-011 14–10–2004 29–01–2011 42/F 45583 7780 107965 823 559 489 533 575 x 1071 1191 1043 KP890746–61
T-012 20–09–2008 03–02–2011 30/F <150 <150 x 1380 NA 1549 1964 x x 1142 1071 x ­
T-013 20–04–2005 02–12–2011 25/F 438 3877 4528 856 580 816 718 502 724 1214 1424 1164 KT152635–37
T-014 28–10–2002 16–02–2011 35/F 2888 4578 x 553 484 376 436 425 x 1000 743 973 KT152638–42
T-015 11–05–2002 25–02–2011 36/F 542 3120 x 920 1000 820 880 830 x 1237 1097 1321 KT152643–47
T-016 22–10–2007 09–08–2011 38/F 1664 1401 x 730 x 653 x x x 1535 1366 x KT152648–49
T-017 20–12–2006 27–09–2011 36/F 5598 x x 504 332 325 x x x 2000 >2000 x KT152650–52
T-018 16–03–2007 29–08–2011 34/M 6645 x 150244 519 563 483 452 446 x 1751 1732 1283 KT152653–56
T-019 31–05–2007 19–09–2011 39/M 63722 x x 238 x x x x x 1379 x x KT152658
T-020 03–12–2008 11–12–2011 35/M <150 489 x 459 x x x x x >2000 x x KT152659
T-021 14–06–2008 14–10–2011 52/M 31410 x x 676 651 641 x x x 884 861 x ­
T-022 20–07–2007 19–12–2011 38/M 6625 46553 x 624 522 558 488 x x >2000 >2000 x KT152660–63
T-023 12–08–2004 23–02–2012 39/F <150 x x 987 x x x x x 1195 x x ­
T-024 19–02–2007 28–02–2012 50/F 541 x x 914 1179 1570 1574 x x 1174 >2000 x KT152664
T-025 11–06–2007 07–03–2012 38/F 1294 4369 x 789 950 693 x x x 1724 1968 x KT152665
T-026 11–07–2007 15–03–2012 54/F 197 <150 974 907 x 1215 x 922 x 1345 1517 1748 ­
T-027 29–04–2005 26–03–2012 36/F <150 x x 1195 630 x x x x 767 x x ­
T-028 25–05–2007 19–04–2012 28/F 162112 x x 398 318 x x x x 885 x x KT152666-68
T-029 31–12–2007 28–04–2012 30/F 1659 1504 x 618 694 599 545 x x 1362 x x KT152669-70
T-030 22–12–2005 03–05–2012 42/F 284879 1E + 06 x 545 410 368 x x x 1352 x x KT152672-73
T-031 28–06–1999 09–06–2012 24/F 753 x x 819 x x x x x 1091 x x ­
(B) The Nellore cohort, n = 35
Subject-ID Enrolment date Age/ Gender Cell count PVL GenBank Accession No.
CD4 CD8 Gag
INDO-SA-NLR2001 26–09–2011 23/F 608 1035 25149 ­
INDO-SA-NLR2002 26–09–2011 32/F 589 927 26186 KT124420–21
INDO-SA-NLR2003 26–09–2011 69/M 1140 1192 548 KT124422
INDO-SA-NLR2004 26–09–2011 43/F 1012 1240 6070 KT124423–24
INDO-SA-NLR2005 26–09–2011 35/F 599 773 5713 KT124425–27
INDO-SA-NLR2006 26–09–2011 46/F 659 1185 662 KT124428
INDO-SA-NLR2007 26–09–2011 40/M 546 912 11986 KT124429–31
INDO-SA-NLR2008 26–09–2011 46/M 1289 1175 3687 KT124432–33
INDO-SA-NLR2010 26–09–2011 32/F 989 1497 251 KT124434–36
INDO-SA-NLR2011 26–09–2011 28/F 582 642 2704 KT124437
INDO-SA-NLR2012 28–09–2011 28/F 1087 1420 6070 KT124438–39
INDO-SA-NLR2014 28–09–2011 55/M 766 >2000 88645 KT124440–41
INDO-SA-NLR2015 28–09–2011 34/F 1019 >2000 21108 KT124442–43
INDO-SA-NLR2016 28–09–2011 29/F 631 1465 26363 KT124444–46
INDO-SA-NLR2017 28–09–2011 39/M 581 1050 8972 KT124447–49
INDO-SA-NLR2018 28–09–2011 35/F 825 1637 6493 KT124450–52
INDO-SA-NLR2019 28–09–2011 35/F 1085 1078 185 KT124453
INDO-SA-NLR2020 28–09–2011 38/M 570 1268 70025 KT124454–56
INDO-SA-NLR2022 28–09–2011 38/M 1489 1470 <150 KT124457
INDO-SA-NLR2023 28–09–2011 28/M 8.2 >2000 <150 ­
INDO-SA-NLR2024 14–10–2011 30/F 984 1279 340 ­
INDO-SA-NLR2025 14–10–2011 30/M 500 825 3423 KT124458–60
INDO-SA-NLR2026 14–10–2011 18/M 1015 1546 8733 KT124461–63
INDO-SA-NLR2028 14–10–2011 34/F 711 1409 24480 KT124464–65
INDO-SA-NLR2029 14–10–2011 35/F 1148 1290 <150 ­
INDO-SA-NLR2030 14–10–2011 39/F 1185 1041 <150 ­
INDO-SA-NLR2031 14–10–2011 50/F 1007 498 <150 ­
INDO-SA-NLR2032 14–10–2011 45/M 671 821 9468 KT124466–68
INDO-SA-NLR2036 14–10–2011 27/M 860 1715 3332 KT124469–70
INDO-SA-NLR2037 14–10–2011 29/M 732 >2000 1505 KT124471–72
INDO-SA-NLR2038 31–10–2011 33/M 669 777 26542 KT124473
INDO-SA-NLR2039 31–10–2011 47/M 925 1111 4563295 KT124474–75
INDO-SA-NLR2040 31–10–2011 29/M 1181 978 <150 ­
INDO-SA-NLR2041 31–10–2011 45/M 888 1237 56445 KT124476–77
INDO-SA-NLR2042 02–12–2011 26/F 1280 >2000 4797 KT124478
  1. Note: Accession Numbers. KP890700-KP890762 and KT152677-686: Full-length gag sequences of six subjects (T002, T004, T006, T008, T009 and T011) at M0 time-point as determined using the plasmid clone sequencing strategy. The rest of the sequences were determined by direct sequencing of the PCR amplicons of the same subjects at the follow-up time-points
  2. M: The month of sample collection at 6 month interval from baseline M0
  3. X: Information not available
  4. −: Failed PCR amplification
  5. PVL: Plasma viral load (number of RNA copies/ml)
  6. CD4 and CD8: cell count (cells/μl)
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BMC Infectious Diseases

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