Table 4 Factors influencing the kinetics of release of asexual parasites in children with early rising asexual parasitaemia

Age

<5 years (n = 36) v

0.3 (0.2–0.3) v

0.17

1 (0.7–1.2) v

0.42

≥5 years (n = 169)

0.2 (0.18–0.2)

1 (0.9–1.1)

Gender

Male (n = 116) v

0.2 (0.17–0.2) v

0.21

1.1 (1–1.3) v

0.02

Female (n = 89)

0.2 (0.2–0.3)

0.9 (0.8–1)

Duration of illness

≤2 days (n = 61) v

0.2 (0.2–0.3) v

0.38

0.9 (0.8–1) v

0.02

>2 days (n = 117)

0.2 (0.2–0.3)

1.1 (0.9–1.2)

Enrolment parasitaemia

≤100000 μL⁻¹ (n = 40) v

0.2 (0.1–0.3) v

0.43

1 (0.8–1.3) v

0.98

>100000 μL⁻¹ (n = 165)

0.2 (0.2–0.3)

1 (0.9–1.1)

Enrolment temperature

≤37.4 °C (n = 51) v

0.3 (0.2–0.3) v

0.21

1 (0.7–1.2) v

0.4

>37.4 °C (n = 154)

0.2 (0.18–0.2)

1 (0.9–1.1)

Haematocrit

<30% (n = 49) v

0.2 (0.2–0.3) v

0.54

1.1 (0.9–1.3) v

0.22

≥30% (n = 156)

0.2 (0.2–0.3)

1 (0.9–1.1)

Fever clearance time

≤1 days (n = 140) v

0.2 (0.2–0.3) v

0.33

1 (0.9–1.1) v

0.43

>1 days (n = 14)

0.2 (0.1–0.2)

0.9 (0.7–1.1)

Parasite clearance time

≤1 days (n = 144) v

0.25 (0.21–0.28) v

0.01

0.8 (0.7 – 0.8) v

<0.0001

>1 days (n = 61)

0.18 (0.14–0.21)

1.6 (1.4–1.8)