Intensified hand-hygiene campaign including soap-and-water wash may prevent acute infections in office workers, as shown by a recognized-exposure -adjusted analysis of a randomized trial

Table 2 Weekly prevalence of reported symptoms of respiratory (RTI) or gastrointestinal tract infections (GTI) infections, and distribution of designated disease episodes in the three trial arms

Type of infection and arm	Number of distinct infection episodes and proportion of weeks with onset^b	Weekly prevalence of reported symptoms
Type of infection and arm		Number and proportion (out of all follow-up weeks^a)	Predictive margin (and 95% credible interval)	Risk ratio (RRa)^c(and 95% credible interval)	Probability that RRa is under 1.0
RTI
Control	974/0.084	1470/0.126	0.130 (0.114, 0.151)	NR
Soap and water	1187/0.079	1646/0.110	0.108 (0.096, 0.122)	0.836 (0.658, 1.031)	0.954
Alcohol rub	1055/0.088	1546/0.129	0.124 (0.109, 0.144)	0.960 (0.755, 1.197)	0.639
GTI
Control	233/0.020	313/0.027	0.025 (0.020, 0.032)	NR
Soap and water	231/0.015	282/0.019	0,019 (0.015, 0.023)	0.740 (0.510, 1.049)	0.960
Alcohol rub	229/0.019	274/0.023	0.023 (0.018, 0.029)	0.902 (0.620, 1.1281)	0.720

NR not relevant
^aTotal numbers of reported person weeks were 11,644, 15,014, and 11,986 in the control, soap and water, and alcohol rub arms, respectively
^bData from reference [14]
^cRRa = risk ratio, ratio of the predictive margin to that of the control arm

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