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Table 2 Association of viral and host variables to quantitative HBsAg concentrations using linear regression

From: Platelet counts modulate the quantitative relationship between hepatitis B viral DNA and surface antigen concentrations: a cross-sectional study of hematological, histological and viral factors

  Univariate Analysis Multivariate Analysis
Variables Regression coefficient 95% CI P Adjusted regression coefficient 95% CI P
Age
  -0.015 (-0.024 ~ -0.006) 0.002 0.002 (-0.009 ~ 0.013) 0.678
Gender-Male
  -0.188 (-0.491 ~ 0.115) 0.224    
ISHAK Fibrosis Stages
  -0.134 (-0.206 ~ -0.061) <0.001 -0.125 (-0.203 ~ -0.48) 0.002
Piecemeal necrosis       
  -0.098 (-0.223 ~ 0.038) 0.156    
Confluent necrosis       
  -0.073 (-0.210 ~ 0.064) 0.293    
Focal (spotty) lytic necrosis, apoptosis and focal inflammation       
  -0.064 (-0.207 ~ 0.078) 0.375    
Portal inflammation
  -0.083 (0.197 ~ 0.031) 0.152    
HBV DNA (log10 IU/ml)       
  0.310 (0.258 ~ 0.363) <0.001 0.267 (0.197 ~ 0.337) <0.001
HBeAg
  0.709 (0.509 ~ 0.909) <0.001 0.301 (0.045 ~ 0.566) 0.021
ALT
  0.000 (0.000 ~ 0.001) 0.23    
AST
  0.001 (0.000 ~ 0.002) 0.144    
Bilirubin       
  -0.121 (-0.372 ~ 0.130) 0.343    
Albumin
  -0.017 (-0.455 ~ 0.422) 0.94    
GGT
  -0.002 (-0.006 ~ 0.001) 0.122    
Platelet
  0.003 (0.001 ~ 0.005) 0.003 0.002 (0.000 ~ 0.005) 0.064
Hemoglobin
  -0.107 (-0.204 ~ -0.010) 0.03 -0.57 (-0.137 ~ 0.023) 0.162
  1. Statistical significant values (P <0.05) were now presented in italic font