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Table 1 Calculation of intrinsic and extrinsic performances of HIV testing by PMTCT site laboratories

From: Feasibility Study of HIV Sentinel Surveillance using PMTCT data in Cameroon: from Scientific Success to Programmatic Failure

 

National Reference Laboratory (NRL SSS-HIV test)

PMTCT sites results

HIV+

HIV−

Total

Test +

a

b

a + b

Test−

c

d

c + d

Total

a + c

b + d

a + b + c + d

  1. \( Reference\;HIV\; Prevalence=100\times \frac{a+c}{a+b+c+d} \)
  2. \( Sensitivity\kern4.56em =100\times \frac{a}{a+c} \)
  3. \( Positive\ Predictive\ Value = 100\times \frac{a}{a+b} \)
  4. \( PMTCT\kern0.24em HIV\kern0.48em rate\kern1.68em =100\times \frac{a+b}{a+b+c+d} \)
  5. \( Specificity\kern4.08em =100\times \frac{d}{b+d} \)
  6. \( Negative\; Predictive\; Value=100\times \frac{d}{c+d} \)