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Table 5 Incidence rate, univariate and multivariate analysis among IPT completed, in-completed and non- exposed patients in public health facilities of Addis Ababa, during 2007-June 2012

From: Effectiveness of isoniazid preventative therapy in reducing incidence of active tuberculosis among people living with HIV/AIDS in public health facilities of Addis Ababa, Ethiopia: a historical cohort study

Patient profile Event/P/Y IR/100P-Y Crude IRR (95% CI) Adjusted IRR(95% CI)
Over all 277/4106 6.7   
IPT completed 7/33.3 0.21 0.03(0.01–0.06) 0.04(0.05–0.07)
IPT in-completed 8/7.8 0.86 0.84(0.36–1.33) 0.89(0.49–1.76)
IPT non-exposed 262/36.49 7.18 1 1
Sex
 Male 138/2822.1 4.89 1.80(1.42–2.28) 1.59(1.20–2.12)
 Female 139/5129.2 2.71 1 1
Age group in year
 <30 103/3038.3 3.39 1 1
 30–39 87/2628.4 3.31 0.98(0.73–1.29) 0.82(0.61–1.11)
 40–49 61/1644.2 3.71 1.09(0.79–1.49) 1.04(0.74–1.47)
 >49 26/637.3 4.08 1.201(0.77–1.82) 1.55(0.95–2.44)
Residence area
 Living out of Addis Ababa 4/135.1 2.96 0.85(0.26–1.99) 0.29(0.09–0.73)
 Living in Addis Ababa 273/7800 3.50 1 1
Religion
 Orthodox 231/6243.2 3.70 0.63(0.20–3.82) 0.29(0.08–1.86)
 Muslim 19/892 2.13 0.36(0.11–2.28) 0.17(0.04–1.13)
 Protestant 25/778.8 3.21 0.55(0.16–3.40) 0.32(0.09–2.12)
 Others* 11/187.7 5.86 1 1
Marital status
 Married 127/3547.5 3.58 0.82(0.46–1.68) 1.22(0.66–2.51)
 Single 72/1889.8 3.81 0.88(0.48–1.81) 1.18(0.63–2.48)
 Widowed 33/1284 2.57 0.59(0.30–1.27) 0.81(0.40–1.76)
 Divorced 35/997.2 3.51 0.81(0.45–1.72) 1.05(0.53–2.27)
 Separated 10/229.9 4.35 1 1
Employment
 Self employed 87/3782.6 2.30 0.03(0.01–0.19) 0.02(0.01–0.12)
 Private Employed 58/1418.1 4.09 0.06(0.02–0.35) 0.03(0.01–0.16)
 Government employed 62/1324.8 4.68 0.07(0.02–0.40) 0.03(0.01–0.19)
 Student 3/66.5 4.51 0.06(0.01–0.48) 0.01(0.002–0.101)
 Non- employed 65/1354.2 4.80 1 1
Educational level
 None educated 42/1707.3 2.46 0.65(0.35–1.33) 1.25(0.62–2.70)
 Primary Completed 106/3028.6 3.50 0.93(0.52–1.83) 1.69(0.89–3.49)
 Secondary Completed 118/2920.8 4.04 1.07(0.60–2.10) 1.76(0.97–3.55)
 Tertiary completed 11/291 3.78 1 1
House Hold size/room no.    0.99(0.89–1.09) 0.98(0.88–1.07)
Baseline WHO stage of HIV/AIDS
 Stage 1 & 2 45/4545.5 0.99 0.14(0.10–0.19) 0.23(0.16–0.31)
 Stage 3 & 4 232/3381.9 6.86   1
Baseline CD4 cells/μl     
 ≤200 211/4169.9 5.06 2.89(2.21–3.85) 1.36(1.02–1.84)
 >200 66/3771.4 1.75   
Baseline weight in Kg
 ≤49 113/2646.4 4.27 1.88(1.12–3.43) 1.63(0.93–3.05)
 50–59 108/3343.7 3.23 1.42(0.85–2.59) 1.19(0.69–2.22)
 60–69 42/1333.3 3.15 1.39(0.78–2.64) 1.06(0.59–2.03)
 >69 14/616.7 2.27 1 1
Baseline OIs
 Yes 194/6278.3 3.09 0.62(0.48–0.80) 1.24(0.95–1.63)
 No 83/1660 5.00 1 1
CPT adherence     
 Good 271/7765 3.49 0.99(0.48–2.51) 0.92(0.44–2.37)
 Fair, Poor & no CPT 2/56.8 3.52 1 1
  1. *others include: catholic, johoba and non belivers