Pneumococcal carriage and antibiotic susceptibility patterns from two cross-sectional colonization surveys among children aged <5 years prior to the introduction of 10-valent pneumococcal conjugate vaccine — Kenya, 2009–2010

Table 3 Number and proportion of pneumococcal isolates from children aged <5 years in Kibera and Lwak, 2009, that are susceptible, intermediate, and resistant by antibiotic (N = 657)

Antibiotic	Susceptible		Intermediate		Resistant
	Break-point μg/ml*	N (%)	Break-point μg/ml*	N (%)	Break-point μg/ml*	N (%)
Penicillin^a	≤0.06	118 (18.6)	0.12–1	500 (79.0)	≥2	15 (2.4)
Chloramphenicol^b	≤4	615 (98.1)	n/a	n/a	≥8	12 (1.9)
Levofloxacin^b	≤2	627 (100)	4	0	≥8	0
Erythromycin^a	≤0.25	625 (98.7)	0.5	1 (0.2)	≥1	7 (1.1)
Ceftriaxone^a	≤1	633 (100)	2	0	≥4	0
Tetracycline^a	≤2	511 (80.7)	4	15 (2.4)	≥8	107 (16.9)
Cotrimoxazole^c	≤0.5/9.5	12 (1.9)	1/19–2/38	58 (9.2)	≥4/76	561 (88.9)
Clindamycin^a	≤0.25	632 (99.8)	0.5	0	≥1	1 (0.2)

*Breakpoints defined using Clinical and Laboratory Standards Institute (CLSI) guidelines 2012. For penicillin, breakpoints for oral penicillin were used
^a24 isolates missing information on susceptibility
^b30 isolates missing information on susceptibility
^c26 isolates missing information on susceptibility

ISSN: 1471-2334