Associations of statins and antiretroviral drugs with the onset of type 2 diabetes among HIV-1-infected patients

BMC Infectious Diseases

Table 3 Incidence of type 2 diabetes according to statin use

Characteristic	Statins users (n = 917)	Non-Statin users (n = 5278)	p-value
Diagnoses of type 2 diabetes	23 (2.5%)	212 (4.0%)	0.025^a
Person-years of follow-up (PYFU) median follow-up (IQR), years	12720 15.4 (8.9–18.1)	51429 8.9 (3.8–15.5)	<0.001^b
Incidence rate of type 2 diabetes (95%CI) per 1000-PYFU	7.1 (4.2–10.1) ^c	3.5 (3.0–4.0)	0.041^d

^a by Chi-square test
^b by Wilcoxon rank-sum test
^c Incidence rate of statin users was calculated using only PYFU effectively spent on statin treatment while their untreated PYFU was added to PYFU of non-statin users
^d by univariate Fine-Gray regression model [HR = 1.58 (95%CI: 1.02–2.46)]

ISSN: 1471-2334