Table 2 Patients characteristics according to statins use
Characteristics | Statin users (n = 917) | Non-Statin users (n = 5278) | p-value |
|---|---|---|---|
Age (years), median (IQR) | 38.6 (32.3–45.9) | 35.1 (30.2–41.1) | <0.001a |
Males, n (%) | 722 (79%) | 4106 (78%) | 0.55b |
White Race, n (%) | 881 (96%) | 4909 (93%) | 0.09 b |
Smoke, n (%) | <0.001 b | ||
 Current/ex-smoker | 395 (43%) | 2088 (39%) | |
 Never | 271 (30%) | 1870 (38%) | |
 Unknown | 251 (27%) | 1320 (23%) | |
Body Mass Index, n (%) | <0.001 b | ||
 Normal (<25 kg/m2) | 409 (45%) | 2137 (41%) | |
 Overweight (25–29.9 kg/m2) | 323 (35%) | 1171 (22%) | |
 Obese (≥30 kg/m2) | 100 (11%) | 289 (5%) | |
 Unknown | 85 (9%) | 1681 (32%) | |
HIV risk factor, n (%) | <0.001 b | ||
 IVDU | 73 (8%) | 1107 (21%) | |
 MSM | 246 (27%) | 1028 (20%) | |
 Heterosexual | 352 (38%) | 1595 (30%) | |
 Other/Unknown | 246 (27%) | 1548 (29%) | |
Ab-anti HCV, n (%) | <0.001 b | ||
 Positive | 136 (15%) | 1564 (30%) | |
 Negative | 721 (77%) | 3143 (60%) | |
 Unknown | 60 (7%) | 570 (11%) | |
HBsAg, n (%) | 0.001 b | ||
 Positive | 42 (5%) | 302 (6%) | |
 Negative | 787 (86%) | 4263 (81%) | |
 Unknown | 88 (10%) | 713 (14%) | |
Years since first HIV-positive test, median (IQR) | 18.0 (11.5–22.8) | 14.1 (7.4–20.7) | <0.001a |
AIDS diagnosis before ART, median (IQR) | 96 (11%) | 532 (10%) | 0.72 b |
Nadir CD4 cell count before ART (cells/μL), median (IQR) | 285 (177–398) | 283 (160–412) | 0.99a |
Baseline Total Cholesterol (mg/dL), median(IQR) | 183 (154–207) (available in 301 pts) | 154 (131–179) (available in 2013 pts) | <0.001 a |
Baseline HDL-cholesterol (mg/dL), median(IQR) | 38 (32–44) (available in 123 pts) | 38 (32–45) (available in 939 pts) | 0.56 a |
Baseline LDL-cholesterol (mg/dL), median (IQR) | 124 (102–150) (available in 111 pts) | 98 (79–117) (available in 878 pts) | <0.001 a |
Baseline Fasting Glucose (mg/dL), median (IQR) | 88 (81–95) (available in 375 pts) | 85 (79–92) (available in 2302 pts) | <0.001 a |
Baseline Triglycerides (mg/dL), median (IQR) | 110 (82–170) (available in 318 pts) | 102 (75–148) (available in 2049 pts) | <0.001 a |
Baseline CD4 cell count (cells/μL), median (IQR) | 300 (186–433) (available in 564 pts) | 307 (171–444) (available in 3119 pts) | 0.75 a |
Baseline HIV-RNA (log10 copies/ml), median(IQR) | 4.72 (4.18–5.15) (available in 421 pts) | 4.74 (4.15–5.20) (available in 2584 pts) | 0.85 a |
Baseline hemoglobin (mg/dl), median (IQR) | 13.9 (12.8–14.8) (available in 403 pts) | 14 (12.7–14.9) (available in 2541 pts) | 0.72 a |
Baseline creatinine (mg/dl), median (IQR) | 0.85 (0.75–0.95) (available in 287 pts) | 0.81 (0.71–0.93) (available in 1952 pts) | 0.017 a |