Phenotypic and molecular detection of the blaKPC gene in clinical isolates from inpatients at hospitals in São Luis, MA, Brazil

Ribeiro, Patricia Cristina Saldanha; Monteiro, Andrea Souza; Marques, Sirlei Garcia; Monteiro, Sílvio Gomes; Monteiro-Neto, Valério; Coqueiro, Martina Márcia Melo; Marques, Ana Cláudia Garcia; de Jesus Gomes Turri, Rosimary; Santos, Simone Gonçalves; Bomfim, Maria Rosa Quaresma

doi:10.1186/s12879-016-2072-3

Table 2 Antibiotic resistance profiles and minimal inhibitory concentrations for fermentative bacilli species

From: Phenotypic and molecular detection of the bla_KPC gene in clinical isolates from inpatients at hospitals in São Luis, MA, Brazil

	fermentative gram-negative bacilli
Antibiotics	K. pneumoniae		E. cloacae		E. aerogenes		S. marcescens		Pantoea spp.		P. mirabilis		R. planticola		R. ornithinolytica		E.coli		A. salmonicida ^a
Antibiotics	%	MIC	%	MIC	%	MIC	%	MIC	%	MIC	%	MIC	%	MIC	%	MIC	%	MIC	%	MIC
amikacin	12	≥64	5.3	≥64	33.3	≥64	80.0	≥64	0.0	16	33.3	≥64	0.0	16	0.0	4	0.0	≤2	0.0	4
ampicillin	100	≥32	100	≥32	100	≥32	100	≥32	100	≥32	100	≥32	100	≥32	100	≥32	100	≥32	100	≥32
amp/sulbac^b	100	≥32	100	≥32	100	≥32	100	≥32	100	≥32	100	≥32	100	≥32	100	≥32	100	≥32	100	≥32
aztreonam	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64
cephalothin	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64
cefepime	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64
cefotaxime	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64
cefoxitin	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64
ceftazidime	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64	100	≥64
ciprofloxacin	93.3	≥4	89.5	≥4	55.6	≥4	0.0	≤0.25	66.7	≥4	66.7	≥4	100	≥4	100	≥4	50.0	≥4	0.0	≤0.5
polymyxin B	10.7	64	0	≤0.5	0.0	≤0.5	100	≥16	0.0	≤0.5	100	≥16	100	≥16	100	≥16	0.0	≤0.5	NT^d	NT^d
gentamicin	52	≥16	68.4	≥16	11.1	≥16	40.0	≥16	33.3	≥16	66.7	≥16	100	≥16	0.0	≤1	50.0	≥16	0.0	≤1
imipenem	85.3	≥32	42.1	≥32	88.9	≥32	80.0	≥16	33.3	≥16	100	≥32	100	≥16	100	≥16	0.0	≤1	100	≥16
meropenem	84	≥32	42.1	≥32	88.9	≥32	80.0	≥16	33.3	≥16	66.7	≥32	50.0	≥16	100	≥16	0.0	≤0.25	100	≥16
ertapenem	100	≥32	100	≥32	88.9	≥32	100	≥8	100	≥8	100	≥32	100	≥8	100	≥8	100	≥8	100	≥8
piper/tazob^c	100	≥128	94.7	≥128	88.9	≥128	100	≥128	100	≥128	66.7	≥128	100	≥128	100	≥128	100	≥128	0.0	16
tigecycline	21.3	≥8	52.6	≥8	22.2	≥8	40.0	≥8	NT^d	NT^d	100	≥8	100	4	0.0	2	0.0	≤0.5	NT^d	NT^d
	75		19		9		5		3		3		2		1		2		1

^a Family Aeromonadaceae
^b amp/sulbac = ampicillin/sulbactam
^c piper/tazob = piperacillin-tazobactam
^d NT = non-tested

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