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Table 2 Logistic regression estimates of the unadjusted and adjusted odds ratios of prevalent tuberculosis in the Western Cape study sites

From: The association of hyperglycaemia with prevalent tuberculosis: a population-based cross-sectional study

Characteristic

Total number (%)

Number (%) with prevalent TB

Unadjusted OR

(95% CI)

P-value#

Adjusteda OR

(95% CI)

P-value#

Overall

11,367 (100)

285 (2 · 5)

-

-

-

-

Random blood glucose concentration (mmol/L)

<5.6

6,068 (53.4)

146 (2.4)

1

0.149 (test for linear trend p = 0.328; test for departure from trend p = 0.121)

1

0.059 (test for linear trend p = 0.098; test for departure from trend p = 0.096)

5.6–6.9

3,464 (30.5)

89 (2.6)

1.06 (0.81–1.39)

1.14 (0.85–1.53)

7.0–8.9

1,269 (11.2)

35 (2.8)

1.14 (0.78–1.66)

1.15 (0.76–1.76)

9.0–11.0

244 (2.2)

2 (0.8)

0.34 (0.08–1.40)

0.42 (0.10–1.76)

>11.0

322 (2.8)

13 (4.0)

1.71 (0.95–3.06)

2.49 (1.29–4.79)

Age (years)

18–24

2,953 (26 · 0)

59 (2 · 0)

1

0 · 059

1

0 · 014

25–29

1,650 (14 · 5)

40 (2 · 4)

1 · 19 (0 · 79–1 · 79)

1.25 (0.80–1.95)

30–34

1,325 (11 · 7)

24 (1 · 8)

0 · 89 (0 · 55–1 · 45)

0.81 (0.47–1.39)

35–39

1,175 (10 · 3)

39 (3 · 3)

1 · 67 (1 · 11–2 · 52)

1.70 (1.07–2.69)

40–49

1,902 (16 · 7)

52 (2 · 7)

1 · 36 (0 · 93–1 · 99)

1.34 (0.87–2.08)

50–59

1,302 (11 · 5)

42 (3 · 2)

1 · 63 (1 · 09–2 · 44)

2.11 (1.31–3.39)

60+

1,052 (9 · 3)

29 (2 · 8)

1 · 39 (0 · 88–2 · 20)

1.72 (0.96–3.06)

Sex

Male

3,743 (32 · 9)

116 (3 · 1)

1

0 · 006

1

0 · 841

Female

7,624 (67 · 1)

169 (2 · 2)

0 · 71 (0 · 56–0 · 90)

0.97 (0.73–1.29)

HIV status

Negative

8,768 (82 · 3)

164 (1 · 9)

1

<0 · 001

1

<0 · 001

Positive

1,889 (17 · 7)

97 (5 · 1)

2 · 83 (2 · 18–3 · 66)

2.96 (2.23–3.93)

Body Mass Index (weight(kg)/height2(m))

Healthy weight (18.5–24.9)

4,302 (39.0)

132 (3.1)

1

<0.001

1

<0.001

Underweight (<18.5)

605 (5.5)

53 (8.8)

2.98 (2.13–4.17)

3.04 (2.14–4.34)

Overweight (25–29.9)

2,609 (23.7)

56 (2.2)

0.69 (0.50–0.95)

0.58 (0.41–0.83)

Obese (≥30)

3,510 (31.8)

34 (1.0)

0.31 (0.21–0.45)

0.25 (0.16–0.39)

Community

SA1

1,131 (10 · 0)

29 (2 · 6)

1

0 · 308

1

0 · 351

SA2

2,193 (19 · 3)

49 (2 · 2)

0 · 84 (0 · 49–1 · 42)

0.85 (0.47–1.55)

SA3 (rural)

190 (1 · 7)

3 (1 · 6)

0 · 61 (0 · 18–2 · 15)

0.51 (0.11–2.39)

SA4

1,618 (14 · 2)

57 (3 · 5)

1 · 33 (0 · 79–2 · 25)

1.49 (0.82–2.73)

SA5

1,164 (10 · 2)

20 (1 · 7)

0 · 64 (0 · 34–1 · 22)

0.71 (0.33–1.51)

SA6 (rural)

2,489 (21 · 9)

65 (2 · 6)

1 · 01 (0 · 61–1 · 67)

1.01 (0.57–1.78)

SA7

1,557 (13 · 7)

40 (2 · 6)

1 · 02 (0 · 59–1 · 75)

1.05 (0.55–1.99)

SA8

1,025 (9 · 0)

22 (2 · 2)

0 · 83 (0 · 45–1 · 52)

0.86 (0.43–1.72)

  1. TB tuberculosis, OR odds ratio, CI confidence interval; All analyses accounted for the two-stage clustered sampling design through use of a logistic regression model with random effects for enumeration area and inclusion of community as a fixed effect; #Likelihood ratio tests; a10,336 participants included in analysis (8 missing data for age; 341 for BMI; 710 for HIV status), adjusted for variables shown plus household socioeconomic position and education