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Table 2 Logistic regression estimates of the unadjusted and adjusted odds ratios of prevalent tuberculosis in the Western Cape study sites

From: The association of hyperglycaemia with prevalent tuberculosis: a population-based cross-sectional study

Characteristic Total number (%) Number (%) with prevalent TB Unadjusted OR
(95% CI)
P-value# Adjusteda OR
(95% CI)
P-value#
Overall 11,367 (100) 285 (2 · 5) - - - -
Random blood glucose concentration (mmol/L) <5.6 6,068 (53.4) 146 (2.4) 1 0.149 (test for linear trend p = 0.328; test for departure from trend p = 0.121) 1 0.059 (test for linear trend p = 0.098; test for departure from trend p = 0.096)
5.6–6.9 3,464 (30.5) 89 (2.6) 1.06 (0.81–1.39) 1.14 (0.85–1.53)
7.0–8.9 1,269 (11.2) 35 (2.8) 1.14 (0.78–1.66) 1.15 (0.76–1.76)
9.0–11.0 244 (2.2) 2 (0.8) 0.34 (0.08–1.40) 0.42 (0.10–1.76)
>11.0 322 (2.8) 13 (4.0) 1.71 (0.95–3.06) 2.49 (1.29–4.79)
Age (years) 18–24 2,953 (26 · 0) 59 (2 · 0) 1 0 · 059 1 0 · 014
25–29 1,650 (14 · 5) 40 (2 · 4) 1 · 19 (0 · 79–1 · 79) 1.25 (0.80–1.95)
30–34 1,325 (11 · 7) 24 (1 · 8) 0 · 89 (0 · 55–1 · 45) 0.81 (0.47–1.39)
35–39 1,175 (10 · 3) 39 (3 · 3) 1 · 67 (1 · 11–2 · 52) 1.70 (1.07–2.69)
40–49 1,902 (16 · 7) 52 (2 · 7) 1 · 36 (0 · 93–1 · 99) 1.34 (0.87–2.08)
50–59 1,302 (11 · 5) 42 (3 · 2) 1 · 63 (1 · 09–2 · 44) 2.11 (1.31–3.39)
60+ 1,052 (9 · 3) 29 (2 · 8) 1 · 39 (0 · 88–2 · 20) 1.72 (0.96–3.06)
Sex Male 3,743 (32 · 9) 116 (3 · 1) 1 0 · 006 1 0 · 841
Female 7,624 (67 · 1) 169 (2 · 2) 0 · 71 (0 · 56–0 · 90) 0.97 (0.73–1.29)
HIV status Negative 8,768 (82 · 3) 164 (1 · 9) 1 <0 · 001 1 <0 · 001
Positive 1,889 (17 · 7) 97 (5 · 1) 2 · 83 (2 · 18–3 · 66) 2.96 (2.23–3.93)
Body Mass Index (weight(kg)/height2(m)) Healthy weight (18.5–24.9) 4,302 (39.0) 132 (3.1) 1 <0.001 1 <0.001
Underweight (<18.5) 605 (5.5) 53 (8.8) 2.98 (2.13–4.17) 3.04 (2.14–4.34)
Overweight (25–29.9) 2,609 (23.7) 56 (2.2) 0.69 (0.50–0.95) 0.58 (0.41–0.83)
Obese (≥30) 3,510 (31.8) 34 (1.0) 0.31 (0.21–0.45) 0.25 (0.16–0.39)
Community SA1 1,131 (10 · 0) 29 (2 · 6) 1 0 · 308 1 0 · 351
SA2 2,193 (19 · 3) 49 (2 · 2) 0 · 84 (0 · 49–1 · 42) 0.85 (0.47–1.55)
SA3 (rural) 190 (1 · 7) 3 (1 · 6) 0 · 61 (0 · 18–2 · 15) 0.51 (0.11–2.39)
SA4 1,618 (14 · 2) 57 (3 · 5) 1 · 33 (0 · 79–2 · 25) 1.49 (0.82–2.73)
SA5 1,164 (10 · 2) 20 (1 · 7) 0 · 64 (0 · 34–1 · 22) 0.71 (0.33–1.51)
SA6 (rural) 2,489 (21 · 9) 65 (2 · 6) 1 · 01 (0 · 61–1 · 67) 1.01 (0.57–1.78)
SA7 1,557 (13 · 7) 40 (2 · 6) 1 · 02 (0 · 59–1 · 75) 1.05 (0.55–1.99)
SA8 1,025 (9 · 0) 22 (2 · 2) 0 · 83 (0 · 45–1 · 52) 0.86 (0.43–1.72)
  1. TB tuberculosis, OR odds ratio, CI confidence interval; All analyses accounted for the two-stage clustered sampling design through use of a logistic regression model with random effects for enumeration area and inclusion of community as a fixed effect; #Likelihood ratio tests; a10,336 participants included in analysis (8 missing data for age; 341 for BMI; 710 for HIV status), adjusted for variables shown plus household socioeconomic position and education