Table 3 HEV IgG seroprevalence in Nepalese blood donors
From: Hepatitis E virus seroepidemiology: a post-earthquake study among blood donors in Nepal
Variable | n tested | HEV IgG seropositive | Univariate Analysis | Multivariate Analysis | |||
|---|---|---|---|---|---|---|---|
n | % (95% CI) | Odds ratio (95% CI) | p value | Odds ratio (95% CI) | p value | ||
Sex | |||||||
 Female | 306 | 109 | 35.6 (30.3–41.0) | a |  | a |  |
 Male | 1,539 | 664 | 43.1 (40.7–45.6) | 1.4 (1.1–1.8) | <0.05 | 1.3 (1.0–1.7) | >0.05 |
Age | <0.05 | Â | <0.05 | ||||
 <25 years | 735 | 155 | 21.1 (18.1–24.0) | a |  | a |  |
 25–34 years | 682 | 330 | 48.4 (44.6–52.1) | 3.5 (2.8–4.4) | <0.05 | 3.5 (2.7–4.5) | <0.05 |
 35–44 years | 315 | 203 | 64.4 (59.2–69.7) | 6.8 (5.1–9.1) | <0.05 | 7.6 (5.5–10.5) | <0.05 |
 45–54 years | 99 | 73 | 73.7 (65.1–82.4) | 10.5 (6.5–17.0) | <0.05 | 10.9 (6.5–18.3) | <0.05 |
 55–64 years | 14 | 12 | 85.7 (67.4–44.2) | 22.5 (5.0–101.4) | <0.05 | 24.6 (4.9–124.3) | <0.05 |
District | <0.05 | Â | <0.05 | ||||
 Bhaktapur | 135 | 74 | 54.8 (46.4–63.2) | 10.8 (5.9–20.1) | <0.05 | 13.5 (7.0–26.1) | <0.05 |
 Kavre | 116 | 52 | 44.8 (35.8–53.9) | 7.3 (3.9–13.7) | <0.05 | 7.0 (3.6–13.8) | <0.05 |
 Kathmandu | 1,435 | 631 | 44.0 (41.4–46.5) | 7.0 (4.1–11.9) | <0.05 | 8.0 (4.6–14.0) | <0.05 |
 Chitwan | 159 | 16 | 10.1 (5.4–14.7) | a |  | a |  |
Donor status | Â | Â | |||||
 Repeat | 1,264 | 606 | 47.9 (45.2–50.7) | 2.3 (1.8–2.8) | <0.05 | 1.4 (1.1–1.7) | <0.05 |
 First time | 581 | 167 | 28.7 (25.1–32.4) | a |  | a |  |
History of Jaundice | |||||||
 Yes | 213 | 119 | 55.9 (49.2–62.5) | 1.9 (1.4–2.6) | <0.05 | 2.0 (1.4–2.7) | <0.05 |
 No | 1,632 | 654 | 40.1 (37.7–42.5) | a |  | a |  |
Family history of jaundice | |||||||
 Yes | 227 | 114 | 50.2 (43.7–56.7) | 1.47 (1.10–1.97) | <0.05 | 1.2 (0.9–1.8) | >0.05 |
 No | 1,618 | 659 | 40.7 (38.3–43.1) | a |  | a |  |
Drinking Water Source | <0.05 | Â | <0.05 | ||||
 Community tap | 273 | 103 | 37.7 (32.0–43.5) | 1.2 (0.8–1.7) | >0.05 | 1.4 (1.0–1.9) | <0.05 |
 Municipality | 940 | 423 | 45.00 (41.8–48.2) | 1.6 (1.2–2.2) | <0.05 | 0.9 (0.5–1.8) | >0.05 |
 Others | 309 | 135 | 43.7 (38.2–49.2) | 1.3 (0.7–2.3) | >0.05 | 1.2 (0.8–1.7) | >0.05 |
 Multiple sources | 63 | 25 | 39.7 (27.6–51.8) | 1.5 (1.1–2.2) | <0.05 | 0.8 (0.6–1.2) | >0.05 |
 Underground | 260 | 87 | 33.5 (27.7–39.2) | a |  | a |  |
Drinking water treatment | >0.05 | Â | Â | ||||
 Boiling | 315 | 117 | 37.1 (31.8–42.5) | a |  |  |  |
 Filtering | 1,030 | 448 | 43.5 (40.5–46.5) | 1.3 (1.0–1.7) | <0.05 |  |  |
 Chemical treatment | 49 | 18 | 36.7 (23.2–50.2) | 1.0 (0.5–1.9) | >0.05 |  |  |
 Multiple methods | 203 | 91 | 44.8 (38.0–51.7) | 1.4 (1.0–2.0) | >0.05 |  |  |
 No treatment | 248 | 99 | 39.9 (33.8–46.0) | 1.1 (0.8–1.6) | >0.05 |  |  |
Vegetarianism | Â | Â | Â | ||||
 Yes | 1,662 | 701 | 42.2 (39.8–44.6) | 1.1 (0.8–1.6) | >0.05 |  |  |
 No | 183 | 72 | 39.3 (32.3–46.4) | a |  |  |  |
Pork consumption | Â | Â | Â | ||||
 Yes | 701 | 323 | 46.1 (42.4–49.8) | 1.3 (1.1–1.6) | <0.05 | 1.3 (1.0–1.6) | <0.05 |
 No | 1,144 | 450 | 39.3 (36.5–42.2) | a |  | a |  |
International travel | Â | Â | Â | ||||
 Yes | 565 | 280 | 49.6 (45.4–53.7) | 1.6 (1.3–1.9) | <0.05 | 0.9 (0.7–1.2) | >0.05 |
 No | 1,280 | 493 | 38.5 (35.9–41.2) | a |  | a |  |