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Table 1 Parameters and plausible ranges in the model

From: Cost-effectiveness analysis of rotavirus vaccination in China: Projected possibility of scale-up from the current domestic option

  Baseline Plausible range for sensitivity analysis Sources
Parameters
 Discount rate 0.03 0 0.03 [31]
 Vaccine coverage 25.3 % 10 % 28.6 % [37, 36]
 Mortality rate 0.0058 % 0.000029 0.000039 [41]
 Rotateq efficacy 98 % 0 0.98 [38]
 Rotateq infected 0.018 % 0 0.00018 [42]
 hospitalization1a 44 % 0 0.44 [22]
 Outpatient1a 28 % 0 0.28 [22]
 Home-care1a 28 % 0 0.28 [22]
 Rotarix infected 0.1 % 0 0.001 [26]
 LLR infected 0.9 % 0 0.009 [41]
 hospitalization3c 0.2 % 0 0.002 [2]
 Outpatient3c 7.9 % 0 0.079 [2]
 home-care3c 91.9 % 0 0.919 [2]
 Rotarix efficacy 96.1 % 0.871 1 [25, 26]
 LLR efficacy 72 % 0.63 0.79 [27]
 Infection rate 78.85 % 0 0.7885 [34]
 home-care2b 32 % 0 0.32 [22]
 hospitalization2 b 33 % 0 0.33 [22]
 Outpatient2b 35 % 0 0.35 [22]
 natural protact1d 77 % 0 0.77 [23]
 natural protact2d 83 % 0 0.83 [23]
Costs
 International vaccinations 200.00 5 250 [16, 17]
 LLR vaccination 24    The national tariff
 Hospitalizations 570.04 0 570.04 [43]
 Outpatient 104.19 0 104.19 [43]
 Home-care 11.52 0 11.52 [44]
Health Effects
 Mortality rate 0.0058 % 0 0.000058 [24]
 QALY(Hospitalization) 0.077 0.075 0.078 [30]
 QALY(Outpatient) 0.081 0 0.081 [30]
 QALY(Home-care) 0.082 0 0.082 [30]
  1. aChildren's first post-infection treatment method (Outpatient, hospitalization, and home-care) selection probabilities
  2. bChildren's second post-infection treatment method (Outpatient, hospitalization, and home-care) selection probabilities
  3. cChildren's third post-infection treatment method (Outpatient, hospitalization, and home-care) selection probabilities
  4. dChildren's own protective efficacy first cured after infection,and Children's own protective efficacy second cured after infection