From: Immune recovery in acute and chronic HIV infection and the impact of thymic stromal lymphopoietin
 |  | Primary HIV (PHI) | Chronic patients CD4 < 200 (LP-AD) | Chronic patients CD4 200–350 (LP-nonAD) | Chronic patients CD4 > 350 (EP) | P* |
---|---|---|---|---|---|---|
N = 14 | N = 20 | N = 24 | N = 42 | |||
Cells/μL | CD4 | |||||
 Baseline | 550 (327)a,b | 55.5 (110)a | 290 (97)b | 510 (172) | < .001 | |
 After 6 months of cART | 740 (375)a,b | 210 (280)a | 450 (190)b | 690 (265) | < .001 | |
 After 12 months of cART | 720 (435)a,b | 340 (170)a | 505 (198)b | 740 (210) | < .001 | |
 After 24 months of cART | 680 (240)a | 269 (160)a | 695 (290) | 820 (317) | < .001 | |
% CD4 Cells | RTE | |||||
 Baseline | 14 (11) | 11 (16) | 20 (15) | 18 (14) | .063 | |
 After 6 months of cART | 16 (11)b | 8 (18) | 27 (15)b | 19 (15) | .006 | |
 After 12 months of cART | 8 (17) | 6 (20) | 17 (25) | 5 (25) | .588 | |
 After 24 months of cART | 18 (9)b | 17 (10) | 28 (11)b | 17 (16) | .009 | |
Naive | ||||||
 Baseline | 43 (20)a | 23 (30)a | 40 (26) | 44 (21) | < .001 | |
 After 6 months of cART | 37 (23) | 22 (31) | 49 (19) | 39 (20) | .031 | |
 After 12 months of cART | 46 (30) | 28 (28) | 49 (19) | 45 (24) | .066 | |
 After 24 months of cART | 36 (12)b | 30 (16) | 55 (16)b | 37 (15) | .002 | |
EM | ||||||
 Baseline | 12 (7) | 17 (14) | 16 (12) | 12 (6) | .009 | |
 After 6 months of cART | 7 (4)a | 18 (11)a | 6 (4) | 7 (4) | .001 | |
 After 12 months of cART | 9 (6)a | 15 (14)a | 7 (5) | 6 (3) | .007 | |
 After 24 months of cART | 9 (4)a | 15 (6)a | 6 (7) | 7 (5) | .043 | |
CM | ||||||
 Baseline | 26 (6) | 20 (22) | 24 (10) | 24 (10) | .597 | |
 After 6 months of cART | 29 (11) | 35 (18) | 27 (15) | 28 (14) | .969 | |
 After 12 months of cART | 26 (8) | 24 (16) | 24 (11) | 25 (10) | .949 | |
 After 24 months of cART | 24 (14) | 30 (23) | 24 (8) | 32 (16) | .784 | |
LD | ||||||
 Baseline | 5 (4)b | 3 (12) | 1 (2)b | 5 (8) | .009 | |
 After 6 months of cART | 8 (11)b | 3 (8) | 1 (3)b | 5 (7) | .012 | |
 After 12 months of cART | 7 (14) | 4 (11) | 2 (3) | 7 (12) | .126 | |
 After 24 months of cART | 9 (16)a,b | 1 (1)a | 3 (2)b | 9 (13) | .038 |