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Table 2 ORs for severe HFMD

From: N-terminal pro-brain natriuretic peptide levels associated with severe hand, foot and mouth disease

Risk factors

Unadjusted OR

(95 % CI)

AdjustedaOR

(95 % CI)

Gender

0.936 (0.535-1.637)

1.105 (0.442–2.759)

Age

0.828 (0.441–1.555)

2.070 (0.692–6.815)

EV71-positivity

9.906 (4.807–20.413)***

19.944 (6.492–61.271)***

Peripheral WBC count

>15 × 109/L

4.926 (2.442–9.938)***

3.428 (1.186–9.914)*

Fasting glucose

>8.3 mmol/L

81.727 (11.045–604.760)***

19.428 (2.236–168.784)**

PCT >0.1 ng/mL

3.737 (2.061–6.777)***

9.084 (3.462–23.837)***

NT-proBNP > 125 pg/mL

11.939 (5.205–27.383)***

16.649 (4.731–58.585)***

  1. HFMD hand, foot, and mouth disease, EV71 enterovirus 71, PCT procalcitonin, NT-proBNP N-terminal of the prohormone brain natriuretic peptide
  2. CI Confidence interval, OR odds ratio. OR was calculated using the mild children as a reference group
  3. aIn multivariate logistic regression model (n = 216), we controlled for age, gender, EV71-seropositivity, WBC, fasting glucose, CK, LDH, PCT and NT-proBNP. After adjusting for potential confounding factors, there was significant difference in EV71 infection, peripheral WBC count, fasting blood glucose, PCT and plasma NT-proBNP levels
  4. *P <0.05, **P <0.01, ***P <0.001
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BMC Infectious Diseases

ISSN: 1471-2334

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