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Table 2 Characteristics associated with MSM achieving viral suppression in the first year of treatment

From: Predictors of viral suppression and rebound among HIV-positive men who have sex with men in a large multi-site Canadian cohort

Characteristic

Viral Suppression , n (%)

No (n = 410)

Yes (n = 2448)

P-value

Province

 British Columbia

140 (34)

714 (29)

0.011

 Ontario

158 (39)

887 (36)

 Quebec

112 (27)

847 (35)

Age (years)

38 (33–44)

40 (34–46)

0.002

Ethnicity

 Caucasian

216 (53)

1104 (45)

0.002

 Black

8 (2)

43 (2)

 Aboriginal

17 (4)

53 (2)

 Other

40 (10)

331 (14)

 Unknown

129 (31)

917 (37)

History of IDU

 No

336 (82)

2219 (91)

<0.001

 Yes

60 (15)

187 (8)

 Unknown

14 (3)

42 (2)

Hepatitis C status

 No

321 (78)

2092 (85)

0.001

 Yes

68 (17)

263 (11)

 Unknown

21 (5)

93 (4)

Era of cART initiation

 2000–2003

152 (37)

577 (24)

<0.001

 2004–2007

127 (31)

804 (33)

 2008–2012

131 (32)

1067 (44)

Number of viral load tests per year

 Less than 3

115 (28)

468 (19)

<0.001

 3–4

188 (46)

1402 (57)

 5–6

48 (12)

312 (13)

 More than 6

59 (14)

266 (11)

Initial 3rd ARV class

 NNRTI

140 (34)

1137 (46)

<0.001

 Unboosted PI

39 (10)

89 (4)

 Boosted PI

194 (47)

1045 (43)

 Other

37 (9)

177 (7)

Initial 3rd ARV

 Nevirapine

41 (10)

211 (9)

<0.001

 Efavirenz

105 (26)

928 (38)

 Lopinavir

73 (18)

351 (14)

 Atazanavir

79 (19)

499 (20)

 Other

112 (27)

459 (19)

NRTI combination

 Tenofovir/emtricitabine

134 (33)

1083 (44)

<0.001

 Zidovudine/lamivudine

114 (28)

480 (20)

 Tenofovir/lamivudine

27 (7)

180 (7)

 Abacavir/lamivudine

58 (14)

410 (17)

 Stavudine/lamivudine

43 (10)

169 (7)

 Other

34 (8)

126 (5)

AIDS-defining illness

 No

307 (75)

1977 (81)

0.006

 Yes

88 (21)

371 (15)

 Unknown

15 (4)

100 (4)

Viral load (log10 copies/mL)

5.00 (4.75–5.00)

4.93 (4.48–5.00)

<0.001

CD4 count (cells/uL)

190 (100–310)

231 (134–327)

0.001