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Table 1 Demographic characteristics of patients with tuberculous spondylitis and culture negative pyogenic spondylitis

From: Comparison of characteristics of culture-negative pyogenic spondylitis and tuberculous spondylitis: a retrospective study

  CNPS (N = 71) TS (N = 94) P-value
Age, mean ± S.D (years) 65.9 (±14.4) 59.2 (±20.0) 0.017
Sex (male, %) 32 (45.1 %) 37 (39.4 %) 0.462
Underlying disease
 Hypertension 34 (47.9 %) 24 (25.5 %) 0.003
 Diabetes mellitus 17 (23.9 %) 16 (17.0 %) 0.271
 Chronic kidney disease 4 (5.6 %) 3 (3.2 %) 0.465
 Congestive heart failure 0 2 (2.1 %) 0.507
 Liver cirrhosis 6 (8.5 %) 1 (1.1 %) 0.043
 Solid tumor 7 (9.9 %) 2 (2.1 %) 0.040
 Hematologic malignancy 1 (1.4 %) 0 0.430
Concomitant corticosteroid use 2 (2.8 %) 1 (1.1 %) 0.578
Epidural procedure within 1 year 19 (26.8 %) 9 (9.6 %) 0.004
Foreign body in affected vertebrae a 8 (11.3 %) 3 (3.2 %) 0.057
Vertebroplasty cement in affected vertebrae 7 (9.9 %) 13 (13.8 %) 0.439
Previous bacteremia within 3 months 3 (4.2 %) 0 0.078
History of tuberculosis 7 (9.9 %) 21 (22.3 %) 0.034
Concurrent pulmonary tuberculosis 0 30 (31.9 %) <0.001
Concurrent extrapulmonary tuberculosis 0 15 (16.0 %) <0.001
  1. Abbreviations: S.D standard deviation, TS tuberculous spondylitis, CNPS culture negative pyogenic spondylitis
  2. aForeign body included Screw or spinal plate for spine fixation
  3. Tuberculous spondylitis was excluded in concurrent extrapulmonary tuberculosis
  4. ‡ †Fisher’s exact test