Table 2 Determinants of mortality among HIV patients on ART using Cox proportional hazard model for Andhra Pradesh and Telangana (2007-12) and Rajasthan (2008-13). CI denotes confidence interval
From: Survival outcomes for first-line antiretroviral therapy in India’s ART program
Andhra Pradesh and Telanganaa | Rajasthanb | |
|---|---|---|
Variables | Hazard ratio (95 % CI) | Hazard ratio (95 % CI) |
Patient level variables | ||
Sex of patient | ||
Male | 1.36 (1.06–1.73) | 1.83 (1.41–2.38) |
Female | 1.00 | 1.00 |
Age of patients (years) | ||
16–29 | 1.00 | 1.00 |
30–49 | 1.00 (0.77–1.29) | 1.00 (0.75–1.34) |
= >50 | 1.24 (0.85–1.79) | 1.25 (0.84–1.88) |
CD4 count at ART initiation (cells/mm3) | ||
< =100 | 3.36 (2.29–4.95) | 3.71 (2.47–5.58) |
101–250 | 1.94 (1.33–2.82) | 1.73 (1.15–2.62) |
>250 | 1.00 | 1.00 |
Co-existing tuberculosis | ||
No | 1.00 | 1.00 |
Yes | 1.42 (1.11–1.81) | 1.31 (1.04–1.67) |
Ever use of alcohol | ||
No | 1.00 | 1.00 |
Yes | 1.57 (1.22–2.02) | 1.42 (1.09–1.86) |
Baseline ART regimenc | ||
STV based regimen with/without EFV | 1.00 | 1.00 |
ZDV based regimen with/without EFV | 0.67 (0.55–0.83) | 0.62 (0.50–0.78) |
Facility level variables | ||
Cumulative ART patient loadd | ||
Below or equal to state average | 1.00 | 1.00 |
Above state average | 0.74 (0.57–0.95) | 1.37 (1.01–1.87) |
Ratio of cumulative ART patients to pre-ART patientse | ||
Below or equal to state average | 1.00 | 1.00 |
Above state average | 0.90 (0.71–1.15) | 1.62 (1.14–2.29) |
Percent of cumulative loss to follow-up patientsf | ||
Category 1 | 1.00 | 1.00 |
Category 2 | 1.16 (0.87–1.54) | 1.22 (0.94–1.58) |
Category 3 | 1.47 (1.06–2.05) | 1.40 (1.00–1.95) |