| TB-IRIS symptoms > 90 days (n = 73) (40.3 %) | TB-IRIS symptoms ≤ 90 days (n = 108) (59.7 %) | p-value for comparison |
---|---|---|---|
Female gender | 50 (68.5) | 66 (61.1) | Â |
Male gender | 23 (31.5) | 42 (38.9) | 0.39 |
Age (years) | 31 (26, 35) | 31 (27, 37) | 0.32 |
WHO stage (n = 181) | |||
 3 | 22 (30.1) | 40 (37) |  |
 4 | 51 (69.9) | 68 (63) | 0.42 |
CD4 count prior to ART (cells/μl) (n = 170) | 57.5 (29, 91.2) | 52 (29.2, 101) | 0.77 |
CD4 count at TB-IRIS (cells/μl) (n = 89) | 117 (71.7, 193.5) | 116 (69, 262.5) | 0.77 |
Previous TB (n = 180) | 15 (20.6) | 30 (28) | 0.34 |
Drug-resistant TB (n = 181)a | 10 (13.7) | 4 (3.7) | 0.02 |
Initial TB diagnosis with extra-pulmonary features (n = 181) | 49 (67.1) | 66 (61.1) | 0.5 |
Initial TB diagnosis with lymph node involvement (n = 178) | 25 (34.2) | 19 (18.1) | 0.02 |
Duration from TB treatment to ART (days)(n = 181) | 58 (33, 84) | 56 (31, 79.5) | 0.8 |
Duration from ART to TB-IRIS onset (days) (n = 181) | 13 (7, 23) | 14 (7, 17) | 0.51 |
Hospitalised at time of TB-IRIS diagnosis (n = 176) | 25 (34.2) | 58 (56.3) | 0.01 |
TB-IRIS lymph node involvement (n = 181) | 40 (54.8) | 31 (28.7) | < 0.0001 |
TB-IRIS pulmonary involvement (n = 181) | 23 (31.5) | 49 (45.4) | 0.07 |
TB-IRIS meningitis (n = 181) | 1 (1.4) | 5 (4.7) | 0.42 |
TB-IRIS abdominal involvement (n = 181) | 59 (80.8) | 81 (75) | 0.37 |
TB-IRIS multisystem involvement (n = 181) | 64 (87.7) | 86 (79.6) | 0.17 |
Pulse rate (n = 120) | 121 (105, 133) | 119 (108, 130) | 0.96 |
C-reactive protein (mg/l) (n = 172) | 111 (74, 157.3) | 95.5 (46.6, 165.7) | 0.14 |
Haemoglobin (g/dl) (n = 113) | 9.0 (8.0, 10.1) | 9.1 (8.0, 10.6) | 0.62 |
White cell count (×109/l) (n = 109) | 5.9 (4.2, 7.2) | 6.0 (4.4, 8.6) | 0.33 |
ALT (IU/l) (n = 157) | 40 (25, 60) | 35 (22, 48) | 0.13 |
Alkaline phosphatase (IU/l) (n = 147) | 164 (114, 261) | 164 (95, 278) | 0.46 |
Corticosteroid treatment for TB-IRIS | 48 (65.8Â %) | 63 (58.3Â %) | 0.35 |