Skip to main content

Advertisement

Table 1 Baseline demographic and clinical characteristics

From: Micafungin versus anidulafungin in critically ill patients with invasive candidiasis: a retrospective study

  Anidulafungin Micafungin P
(n = 30) (n = 33)
On admission
 Age (years) 59 (20) 62 (20) 0.36
 Gender (male)a 19 (63) 26 (79) 0.18
 APACHE II score 26 (10) 23 (8) 0.13
 SOFA score 10 (9) 9 (3) 0.63
 Reasons of ICU admissiona    0.14
  Suspected sepsis 9 (30) 11 (33)  
  Respiratory failure 2 (7) 6 (19)  
  Renal failure 1 (3) 0 (0)  
  Liver failure 4 (13) 0 (0)  
  CPR 2 (7) 2 (6)  
  Shock 5 (17) 3 (10)  
  Postoperative 7 (23) 11 (34)  
At start of echinocandin
 Risk factors for invasive candidiasisa
 Neutropenia 3 (10) 2 (6) 0.57
 Broad spectrum antibiotics 18 (60) 15 (45) 0.25
 Immunosuppression 4 (13) 3 (9) 0.60
 Steroids 16 (53) 12 (36) 0.18
 TPN 4 (13) 11 (33) 0.07
 Recent Surgery 8 (27) 15 (45) 0.13
 DM II 11 (37) 7 (21) 0.18
 Malignancy 5 (17) 11 (33) 0.13
 Transplant 5 (17) 4 (12) 0.61
 CVVH 19 (63) 7 (21) 0.001
 CVC 29 (97) 29 (88) 0.20
 Mechanical ventilation 27 (90) 32 (97) 0.26
Duration between admission and start echinocandin (days) 3 (4) 2 (2) 0.17
  1. Numbers (percentage) aor median (interquartile range), where appropriate
  2. List of abbreviations: APACHE II Acute Physiology and Chronic Health Evaluation II, CPR cardiac pulmonary resuscitation, CVVH continuous venovenous haemofiltration, CVC central venous catheter, DM II diabetes mellitus type II, ICU intensive care unit, TPN total parenteral nutrition